It is estimated by the American Heart Association that nearly 1 in 5 Americans are candidates for increased chance of heart disease, liver failure, and other serious health complications due to high cholesterol levels. While this is one of the most dangerous and prevalent health concerns facing the US, it is also one that is moderately easy to manage. As Americans become more informed of the importance of maintaining a healthy lifestyle, they are increasingly exposed to advertisements touting the successes of the prescription drug industry in remedying this problem. Indeed, there are several anti-hyperlipidemic (raised or abnormal levels of lipids (fatty molecules) due to the influence of cholesterol) medications available on the market. In fact, almost 30 million prescriptions are written each year for cholesterol lowering drugs, accounting for $20 billion in annual sales for the pharmaceutical industry.
The cholesterol cure-all for the pharmaceutical industry came in the form of a kind of drugs called statins. Initially, statins were prescribed in a pharmaceutical regimen designed to fight high cholesterol. Enzymes, which are inhibited by statins lowering cholesterol, stimulate bad cholesterol, also known as LDL, in the liver and thus create an increase of LDL clearance from the blood stream. Results are almost immediate; within a week, the first results of the drug are apparent, but after only four to six weeks, the drugs effect is maximized. It is considered a popular option because the LDL levels are usually reduced anywhere from 30 percent to 50 percent.
From Schering-Plough, which is a chemical research company, as well as Merck, a drug manufacturing company, comes a new anti-cholesterol prescription drug. Zetia, known chemically as Ezetimibe, is an anti-hyperlipidemic medication which is used to lower cholesterol levels. Available as an alternative to statin therapy is Zetia. It acts by decreasing cholesterol absorption in the intestine. Zetia has also been combined with statin therapy in a single pill marketed as Vytorin.
At the beginning of 2008, a report was released showing the adverse affects of Zetia, where growth of plaque occurred, was released by a national newspaper. The ENHANCE trial from the two companies ended in the middle of 2006, with results not scheduled for relase until nearly a year later in March 2007. After the news reported several missed deadlines from the companies, they agreed to publish the results. Additionally, the American College of Cardiology stated in their press release for the ENHANCE study that, "The results of the trial show no benefit from the combination of ezetimibe (Zetia) and simvastatin (sold together as Vytorin) over simvastatin alone in terms of affecting the rate of atherosclerosis(fatty plaque) progression." They went on to say that, "this study deserves serious thought and follow-up."
The evidence of some less scrupulous actions continues. A congressional investigation into the companys' actions was announced. The delayed results and the questionable study surrounding Zetia have led many to question its worth on the pharmaceutical market.
If you or anyone you know has taken Zetia and is concerned about possible Zetia side effects or lower Zetia effectiveness, it may be in your best interest to contact a Zetia law firm or a Zetia lawyer for counsel on Zetia and a possible Zetia lawsuit.
Everyone has cholesterol; it is just that some people have higher levels than others. The people who have high cholesterol have to worry about it affecting their lives and the possibility it could put them at risk for coronary heart disease. Luckily there are different drugs that are available to treat and ensure that the reduction of cholesterol is possible. One such drug is Zetia, this article will examine its purpose and benefits.
We all have cholesterol it just depends on the amount in our bodies. There are two types, which are good cholesterol and bad cholesterol. These are two naturally occurring substances in our body and we produce it naturally and also absorb it through food. Where there is too much bad cholesterol, then there is a chance it could affect the blood vessels in the body. It could either harden arteries or cause plaque build up which makes them smaller. The result of all of this is the possibility in the increase and chance of heart disease.
Zetia is a name brand prescription drug whose generic brand is Ezetimbe. The main role of Zetia is for the reduction of bad cholesterol in the body. The body has two types of cholesterol good and bad, and it is the bad that is associated with the various heart disease and other conditions. Zetia works by reducing the amount of protein in the blood. Protein is used to make cholesterol and stopping one of its creators is a good start. Zetia also works by blocking the cholesterol we may get from eating certain foods. It works in the digestive tract to ensure this is done properly. Often times Zetia is taken in combination with statins. Statins are also used to reduce the amount of cholesterol in the body. Zetia also works with a good diet and good exercise.
Like many medication, Zetia might have some adverse side effects. The mild ones might be headache, diarrhea, dizziness, personality changes, memory loss, tiredness and stomach pain and others to name a few. These are just a few of the mild effects. You can also have muscle pain and weakness along with fatigue, and chest pains. If an individual experiences any of these symptoms they need to see a health care professional immediately. Some people can have an allergic reaction to the use of this drug, it is not widespread, but it is still possible. Symptoms of an allergic reaction are swelling, rashes, and trouble breathing. Like all other side effects, if an individual experiences anything like this, they should report to their doctor.
Both Peter Kent & James Dalton are contributors for EditorialToday. The above articles have been edited for relevancy and timeliness. All write-ups, reviews, tips and guides published by EditorialToday.com and its partners or affiliates are for informational purposes only. They should not be used for any legal or any other type of advice. We do not endorse any author, contributor, writer or article posted by our team.
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