According to the National Digestive Disease Information Clearinghouse (NDDIC), ?Chrones Disease Crohn's disease is an inflammatory bowel disease, the general name for diseases that cause swelling in the intestines. Crohn's disease can affect any area of the GI tract, from the mouth to the anus, but it most commonly affects the lower part of the small intestine, called the ileum. The swelling extends deep into the lining of the affected organ. The swelling can cause pain and can make the intestines empty frequently, resulting in diarrhea.?

Chrohn's disease afflicts around 500,000 people in the United States. Symptoms experienced by those with the disease include abdominal cramps, persistent diarrhea, fever, pain, and fatigue.

According to the FDA, ?Humira works to reduce levels of human tumor necrosis factor (TNF) alpha, a chemical that plays a role in abnormal responses from the body's immune system.?

Most people infected with the disease are diagnosed between the ages of 15 and 35. Some of the side affects of Humira include serious risk of infection such as tuberculosis or blood infections. Less severe side affects include upper respiratory infections, sinusitis, and nausea.

Humira was approved originally by the FDA to treat Psoriatic Arthritis in October of 2005 and was later approved to treat moderate-to-severe rheumatoid arthritis.

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