Choose the Right Blog Software
The right blog CMS makes a big difference. If you want to set yourself apart, I recommend creating a custom blog solution - one that can be completely customized to your users. In most cases, WordPress, Blogger, MovableType or Typepad will suffice, but building from scratch allows you to be very creative with functionality and formatting. The best CMS is something that's easy for the writer(s) to use and brings together the features that allow the blog to flourish. Think about how you want comments, archiving, sub-pages, categorization, multiple feeds and user accounts to operate in order to narrow down your choices. OpenSourceCMS is a very good tool to help you select a software if you go that route.

Tag Your Content
Technorati is the first place that you should be tagging posts. I actually recommend having the tags right on your page, pointing to the Technorati searches that you're targeting. There are other good places to ping - del.icio.us and Flickr being the two most obvious (the only other one is Blogmarks, which is much smaller). Tagging content can also be valuable to help give you a "bump" towards getting traffic from big sites like Reddit, Digg & StumbleUpon (which requires that you download the toolbar, but trust me - it's worth it). You DO NOT want to submit every post to these sites, but that one out of twenty is worth your while.