Because the cause of tuberculosis is obviously seated in the environment and social context of a person, a vaccine against it could not be very helpful. Some persons are protected against tuberculosis because they develop infections with other mycobacterias, this was observed in children who drank unpasteurised milk that developed forms of bovine tuberculosis but not the human type, for some people that is worse because they develop the mycobacterial disease of leprosy.

The BCG vaccine is an attenuated form of the attenuated bacillus, after being inoculated the primary infection appears and in consequence the immunogenic (ability to cause an immune response) response. BCG induces also tuberculin sensitivity, so it is quite easy to determine new cases of tuberculosis using this method. The vaccine also interferes with the resistance created by exposure to nonpathogenic mycobacteria, is contributing to the resistance of tuberculosis to all of the drugs currently used to treat it. Studies conducted in Madras, South India and UK school children showed that most of those vaccinated with BCG got tuberculosis than those who had not been vaccinated.

Other trials in the United States varied in protection from zero to 75%. It has been observed that where is needed, it doesn't work. A healthy diet with lots of clean water, fresh air and exercise will make us strong so that we will not be susceptible to tuberculosis. A healthy diet with lots of clean water, fresh air and exercise will make us strong so that we will not be susceptible to tuberculosis. . Allowing ourselves the time and the space to balance our emotions and nurture our relationships with others is very important for our health, so let's take that time for us and for our inner soul. To understand how a vaccinate actions on our cels and on the bacterias cells we have to understand how mycobacterias invade our organisms and what desequillibriums make on our immune system. This may be the most important information to be taken into consideration when developing a vaccine against tuberculosis.

The correlation between dose of BCG and protection against tuberculosis in humans is still unknown. Despite all the drugs available today, TB is still a problem in developing nations. The highest incidences are in countries in Africa, Asia, and Latin America with low gross national products. The fight against this microorganism first begun when Robert Cook discovered the mycobacteria and later when vaccines and anti-tuberculosis appeared. After the tuberculosis bacteria have been inhaled they reach the lungs and, within approximately six weeks, a small infection appears that rarely gives any symptoms. This is called a primary infection. Some people remain only with this prime infection for the whole of their life, but others develop the active tuberculosis and may get even re-infected or the tuberculosis gets re-activated.