Laxatives promote bowel emptying. Nonprescription laxatives are frequently misued due to lack of understanding of normal bowel function. Restrict self ­ medication to short-term therapy of constipation. Chronic use of laxatives (particularly stimulants) may lead to dependence. Prior to laxative use, consider living habits affecting bowel function including disease state and drug history. Rational therapy and prevention of constipation include: Adequate fluid intake (4 to 6 glasses of water daily), proper dietary habits including sufficient bulk or roughage, responding to the urge to defecate and daily exercise.

Type of Drug

Hyperosmolar laxatives.

How the Drug Works

Glycerin irritates the colon and draws water into the colon, stimulating bowel movements.

Uses

For short-term treatment of constipation.

To treat constipation in infants and children.

Frequent use of laxatives and inadequate fluid can cause an imbalance in fluid and electrolyte levels. Symptoms may include muscle cramps, muscle weakness or dizziness.

Rectal bleeding or failure of the laxative to produce a bowel movement can indicate a more serious condition which requires medical attention.

Children: Physical manipulation of a glycerin suppository in infants will usually promote bowel movements. Because of this, side effects are usually minimal.

Side Effects

Every drug is capable of producing side effects. Many patients experience no, or minor, side effects. The frequency and severity of side effects depends on many factors including dose, duration of therapy and individual susceptibility. Possible side effects include:

Circulatory System: Pounding of the chest (palpitations).

Other: Bowel cramping; stomach cramps; irritation of the rectal area; diarrhea; nausea; vomiting; weakness; dizziness; fainting; sweating; bloating; gas; excessive bowel activity.

Guidelines of Uses

Laxative use is only a temporary measure. Do not use longer than one week. Stop use of these products when normal bowel habits return. Prolonged frequent or excessive use may result in dependence or electrolyte imbalance.

Suppositories- Insert one suppository high in the rectum and retain 15 minutes. It does not need to produce laxative action.