Mexican cuisine is known for its intense and varied flavors, colorful decoration, and the variety of spices that it has. Mexican gastronomy, in terms of diversity of appealing tastes and textures, is one of the richest in the world, rich in proteins, vitamins, and minerals, though some people unaccustomed to eating it characterize it as greasy and excessively spicy.

When Spanish conquistadores arrived in the Aztec capital Tenochtitlan (on the ruins of which Mexico City was built), they found that the common people's diet consisted largely of corn-based dishes with chilis and herbs, usually complemented with beans and squash. Later on, the conquistadores added to their original diet of rice, beef, pork, chicken, wine, garlic, and onions that they brought with them from Spain to the indigenous foods of pre-Columbian Mexico (including chocolate, maize, tomato, vanilla, avocado, papaya, pineapple, chile pepper, beans, squash, sweet potato, peanut and turkey). The totopo (a deep-fried chip of corn tortilla) may have been created as part of this cuisine.

Most of today's Mexican cuisine is based on pre-hispanic traditions, including the Aztecs and Maya, combined with culinary trends introduced by Spanish colonists. Quesadillas, for example, are a flour or corn tortilla with cheese (often a Mexican-style soft farmer's cheese such as Queso Fresco), beef, chicken, pork, etc. The indigenous part of this and many other traditional foods is the chile pepper. Foods like these tend to be very colorful because of the rich variety of vegetables (among them red peppers, green peppers, chiles, broccoli, cauliflower, and radishes) and meats in Mexican food. There is also a sprinkling of Caribbean influence in Mexican cuisine, particularly in some regional dishes from the states of Veracruz and Yucatan. The French occupation of Mexico also yielded some influences as well: the bolillo, a Mexican take on the French roll, certainly seems to reflect this.

Mexican food varies by region, because of local climate and geography and ethnic differences among the indigenous inhabitants and because these different populations were influenced by the Spaniards in varying degrees. The north of Mexico is known for its beef production and meat dishes; southeastern Mexico, on the other hand, is known for its spicy vegetable and chicken-based dishes. Veracruz-style is a common method of preparing seafood.

There are also more exotic dishes, cooked in the Aztec or Maya style, with ingredients ranging from iguana to rattlesnake, deer, spider monkey, and even some kinds of insects. This is usually known as comida prehispanica (or prehispanic food), and although not very common, is relatively well known.

Mexican cuisine has combined with the cuisine of the southwest United States to form Tex-Mex cuisine.

One type of food that is commonly mistaken for Mexican food is New Mexican cuisine, which can be found in, of course, New Mexico, USA.