Rheumatoid arthritis is a systemic disease, involving other organs, whereas osteoarthritis is limited to the joints. Over time, both forms of arthritis can be crippling. SLE Systemic Lupus erythematosus and rheumatoid arthritis (RA). The etiology of cardiovascular disease probably involved an interaction between risk factors traditional and inflammation induced immune-mediated vascular injury, and hormonal and treatment-related factors.

autoimmune and chronic inflammatory nature of both RA and SLE may contribute to atherogenesis. However, there are enough differences in the pathogenesis, organ involvement, and the modalities of treatment of SLE and RA suggest that the differences may exist in the development of atherosclerosis in each of these diseases

Entries the disease is often progressive, with fatigue, morning stiffness (with a duration of more than one hour), diffuse muscle pain, loss of appetite and weakness. Finally, joint pain appears, with warmth, swelling, tenderness, and stiffness of the joint after inactivity.

The cause of rheumatoid arthritis (RA) is unknown. However, RA involves an attack on the body's own immune cells (autoimmune disease). Different cases may have different causes. Infectious, genetic and hormonal factors may play a role.RA usually affects the joints on both sides of the body also -- wrists, fingers, knees, feet and ankles are the most affected.

Difformites result from the destruction of cartilage, bone erosions, and tendon inflammation and fracture. A joint life-threatening complications can occur when the cervical spine becomes unstable as a result of RA.Rheumatoid arthritis is a systemic autoimmune disease that attacks the first synovium, a connective tissue membrane that lines the cavity between joints and secret liquid lubrication.

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