What is Remicade? Remicade, better known as Infliximab, is part of a group of medications called Biological Response Modifiers or TNF (tumor necrosis factor) Blockers. Remicade is a compound created from living organisms and their products - proteins, antibodies, etc. Remicade is designed to improve the body's natural response to disease, by soothing certain parts of the immune system that is thought to be aggravating the condition and causing symptoms.

Studies have found Remicade successful at helping many moderate to severe Crohn's sufferers find relief from their symptoms and achieve remission. Some researchers believe Remicade is an effective treatment because it binds and blocks the effects of TNF-alpha, one of the proteins used to create inflammation.

Remicade is often prescribed to those not responding to steroid or other Crohn's treatment. Remicade is not a steroid drug, therefore, it may also help a Crohn's sufferer reduce or stop steroid treatment which can have unpleasant side effects.

Is Remicade safe for everyone? No. Remicade can lower the body's blood cells which help fight infections. Thus, it is easier for a person to catch infections just by being around those who are ill. It also increases the risk of injury and bleeding more than normal.

In addition, Remicade can increase the risk of developing particular types of cancer such as skin cancer, breast cancer and colon cancer. It also increases the risk of autoimmune disorders like lupus

Remicade isn't recommended for people who have:

• Congestive heart failure
• Chronic obstructive pulmonary disease
• Tuberculosis or previous case(s)
• Hepatitis B
• Seizure or epilepsy
• Cancer history
• A disease that affects the muscles or nerves (IE. Multiple sclerosis)
• A current or recent infection

Children under 6 years of age can not use Remicade, and pregnant women or breastfeeding mothers should talk to their doctor before considering treatment. Furthermore, you should never receive a “live” vaccine when on Remicade, and inform your doctor of any drug allergies.

What are the side effects of Remicade? The following are side effects you need to be aware of including, but not limited to -

Common side effects: stuffy nose; sinus pain; stomach pain; mild skin rash, and headache.

Serious side effects: shortness of breath even after little exertion, swollen feet or ankles; hair loss; skin rash that appear red, purple or scaly; joint or muscle pain; sores in the mouth; feeling numb or tingling; weakness in the arms and legs; vision problems; pain or burning sensation when urinating; nausea; stomach pain; mild fever; dark urine; clay-colored stools; loss of appetite; jaundice and seizures.

Signs of allergic reaction: hives; trouble breathing; Swelling in the face, lips, tongue or throat.

Signs of an infection while on Remicade: fever; flu-like symptoms; soar throat; weight loss; chest pain; chronic cough; coughing blood; pale skin; unusual weakness; bruising or bleeding easily.

Should you experience any serious side effect, allergic reaction or signs of infection seek medical attention immediately and notify your doctor. Also, be sure to notify your doctor if you experience common side effects or side effects not listed.

How is Remicade administered? Remicade is administered by a health care provider, usually every 2 – 8 weeks, and is injected into the patient with a needle. Remicade is injected slowly and treatment is about 2 hours. Those who become experienced with the treatment may be allowed to treat themselves at home, but self-treatment requires confidence and effective understanding.

If Remicade is a treatment that interests you, talk to your doctor and discuss all risks.