Pick's Disease is the result of a build-up of protein in the affected areas of the brain. Pick's disease is rare. It is more common in women than men. Pick disease occurs in a younger age group than dementia of the Alzheimer type. People with Pick's disease tend to behave inappropriately in different social settings. The accumulation of abnormal brain cells, known as Pick's bodies, eventually leads to changes in character, socially inappropriate behavior, and poor decision making, progressing to a severe impairment in intellect, memory and speech. The changes in behavior continue to get worse and are often?one of the most disturbing symptoms of the disease. Behavior modification may help some people control unacceptable or dangerous behaviors. In some cases, cognitive function may be improved by stopping or changing medications that worsen confusion or that are not essential to the care of the person. This may include medications such as anticholinergics, analgesics , cimetidine, central nervous system depressants, and lidocaine. Medication to control behaviors that can be dangerous to oneself or others. Antidepressants known as selective serotonin reuptake inhibitors (SSRIs) may offer some relief from apathy and depression. Some patients may need hearing-aids, glasses, cataract surgery , or other treatments.
Causes of Pick Disease
Common Causes and Risk factors of Pick Disease
Longstanding high blood pressure.
Head trauma
High levels of homocysteine.
Female gender because women usually live longer than men.
Schizophrenialike thought disorder.
Signs and Symptoms of Pick Disease
Common Sign and Symptoms of Pick Disease
Lack of muscle coordination.
Brain degeneration.
learning problems.
Loss of muscle tone.
Increased sensitivity to touch.
Spasticity.
Feeding.
Swallowing difficulties.
Enlarged liver and spleen.
Treatment of Pick Disease
Common Treatment of Pick Disease
Behavior modification may help some people control unacceptable or dangerous behaviors.
Many different types of medications have been or are being tried in dementia. One group of drugs used in Alzheimer disease, the cholinesterase inhibitors.
Medication to control behaviors that can be dangerous to oneself or others. Antidepressants known as selective serotonin reuptake inhibitors (SSRIs) may offer some relief from apathy and depression.
Some patients may need hearing-aids, glasses, cataract surgery , or other treatments.
Anti-inflammatory drugs are being tried on the premise that inflammation is one cause of the brain damage in Pick disease.
Hormone replacement therapy has been given to some women who have been through menopause and have dementia.
Education and other forms of intellectual challenge may help protect people against the disease.
High sugar content foods may need to be restricted in some patients with carbohydrate craving, which may indicate Kl?ver-Bucy syndrome.
Peyronie's disease is an acquired inflammatory condition of the associated with penile curvature and, in some cases, pain. The exact cause of Peyronie's Disease is unknown but several theories have been proposed. The disease is characterized by a hard, fibrous layer of scar tissue (plaque) that usually develops under the skin on the upper or lower side of the Cases of Peyronie's disease range from mild to severe. Symptoms may develop slowly or appear overnight. In Peyronie's disease, dense, fibrous scar tissue forms in the tunica albuginea. Some patients who do not have pain with erection have tenderness on palpation of the indurated plaque. It begins as a localized inflammation and can develop into a hardened scar. Men with Peyronie's disease usually seek medical attention because of painful erections and difficulty.
The onset of signs of the Peyronie's disease can be sudden or slow and can vary in severity. A number of authors believe that Peyronie's disease results, in part, from trauma. Because Peyronie's disease doctors have historically classified the condition as a form of impotence, currently referred to as erectile dysfunction. There is no cure for Peyronie's disease. In many cases, pain caused by Peyronie's disease may decrease after a short period of time. Ten percent of men with Peyronie's Disease have a condition called Dupuytren's contracture which is similar to a trigger finger. Peyronie's disease may shrink or disappear without treatment, medical experts suggest waiting a full year before attempting to correct it surgically.
Causes of Peyronie's disease
The common causes and risk factor's of Peyronie's disease include the following:
Injury
Psychological conditions.
Heredity.
Collagen abnormality.
Neurologic conditions.
Diabetes mellitus.
Smoking.
Symptoms of Peyronie's disease
Some sign and symptoms related to Peyronie's disease are as follows:
Painful erection.
Narrowing of the diameter of your during erection.
Painful erections and difficulty.
A thick band of hard tissue on one or more sides.
Curve in the during erection.
Bend in the with erection.
Hardened tissue (plaque).
Treatment of Peyronie's disease
Here is list of the methods for treating Peyronie's disease
Medications (such as verapamil, potassium aminobenzoate [Potaba], colchicine, or injected steroids) and vitamin E may help treat pain and improve function.
In some cases, use of a penile prosthesis may be used to help maintain an erection.
Shock wave lithotripsy has also been used to treat Peyronie's disease.
Symptoms may go away somewhat with radiation therapy or corticosteroid injections into the fibrous band of tissue.
Vitamin E is also sometimes used.
Peyronie's disease has been treated with some success by surgery.