A new standard in antioxidant activity, Phloretin CF ™ and C E Ferulic ® represent a new class of preventive and corrective topical antioxidant treatment. After five years of extensive research, SkinCeuticals developed this patent-pending breakthrough technology combining the newly-discovered, broad-range power of phloretin with vitamin C and ferulic acid in a biodiverse formulation to divide and conquer sources of damage at every level.

Ploretin CF ™, a broad-spectrum treatment, protects against not only free radicals, but the range of other reactive molecules known to cause damage and DNA mutations among the integral cell types. In addition, it corrects existing damage by stimulating the synthesis of essential proteins and fibers and accelerating cell turnover. The result—a strengthened support structure on the inside and a more youthful, firm, radiant appearance on the outside.

Derived from the bark of fruit trees such as apple, grapefruit, and pear, phloretin is a broad-spectrum molecule newly identified for its antioxidant properties and recently, for use as a pigment-regulating and penetration-enchaining agent in the medical community.

Phloretin’s unique molecular structure is responsible for potent antioxidant activity in peroxynitrite scavenging and in the inhibition of lipid peroxidation. It also displays a wide range of bioactivity such as anticancer, antifungal, antibacterial, antiviral, and anti-inflammatory.

Freckles, age spots, wrinkles, laxity, blotchiness, mottled complexion, and even skin cancer can be traced to sun exposure and increased reactive oxygen species (ROS) levels within our skin. The type and severity of skin depend on a combination of each individual’s genetic makeup, their history of UV radiation exposure, and the intensity of that exposure. Therefore the type of antioxidant treatment needed depends on each individual as well.

Ploretin CF ™ is optimal for:

- Diminishing age spots and other forms of hyper pigmentation
- Accelerating cell renewal
- Improving laxity
- Retexturizing skin
- Oily, problematic, and normal skin

C E Ferulic ® is optimal for:

- Replenishing lipids
- Stimulating collagen synthesis
- Reducing fine lines and wrinkles
- Dry, combination, and normal skin

Lifestyle choices as well as daily exposure to environmental elements produce damaging ROS such as free radicals, oxygen ions, and peroxides in our skin leading to multiple pathways of oxidative stress. Many skin treatments have become increasingly popular to attempt to combat this damaging stress on skin, such as skin peels. San Diego () and North County San Diego, CA boasts several top of the line skin care treatment clinics that offer skin peels.

In controlled clinical studies of Phloretin CF ™, results show reduction of fine lines, wrinkles, laxity, mottled texture, and age spots for dramatically healthier, stronger, and visibly radiant skin beginning as early as four weeks.

The broad-spectrum activity of Phloretin CF ™ effectively quenches the range of ROS in multiple steps of the oxidative pathway. Bio market studies show Phloretin to be a powerful and biodiverse combination that protects the integral cell types by neutralizing the range of ROS in multiple steps of the oxidative pathway.

Phloretin helps protect against damage and DNA mutations which can prevent healthy cell regeneration and lead to signs of photodamage including fine lines, wrinkles, loss of elasticity, discoloration, and even skin cancer. Skin Brightening System () is one of the services offered to aid in the war against these skin ailments.

Phloretin protects integral cell types at various levels of the skin by shielding keratinocytes, melanocytes, and fibroblasts from damage and DNA mutations. These cell types are essential for maintaining the skin’s natural balance and have a tremendous capacity to protect and repair the skin.

In addition, phloretin preserves fibroblasts to stimulate collagen and elastin synthesis and maintains balance of the extra-cellular matrix. By preventing oxidative stress and regulating melanocytes to control pigmentation, integral cells are protected that are responsible for accelerated cell renewal and the skin’s natural repair processes.