It's now being examined and debated with new urgency, thanks to the threat of a bird flu pandemic.
What can the 1918 flu tell us about the current H5N1 strain of bird flu?
According to evolutionary biologist Paul Ewald, author of Evolution of Infectious Disease and Plague Time: How Stealth Infections Cause Cancers, Heart Disease and Other Deadly Ailments (both great books well worth reading), the 1918 flu was so much more lethal than ordinary flu because it appeared and evolved at the Western Front of World War I Europe's brutal trench war.
The more advantageous it is for infections to keep us alive and feeling well enough to walk around, the safer they are. The common cold is irritating but we can still go to work with it -- the better to sneeze and spread cold germs to our co-workers.
The more advantageous it is for infections to destroy us, the more they will destroy us. Malaria makes us so sick because it spreads by mosquitoes -- who find it easier to bite people who're too sick to swap the mosquitoes. Who then go spread the infection to a healthy person.
During the 1918 flu, soldiers in Europe lay sick in crowded trenches where they easily spread the flu to other soldiers even though they were too sick to walk and many soon died. When transported to medical care, they were crowded into trucks and train cars with other sick and wounded soldiers. And arrived at military hospitals crowded with more sick and wounded soldiers.
Therefore, the 1918 flu virus had every evolutionary incentive to evolve into a strain highly lethal to people.
But is that the whole story? According to Ewald, we are not in danger of a bird flu pandemic -- or at least, not one as deadly as 1918 -- because there is no similar war going on today.
So should we all forget about bird flu and start worrying only about Iran?
Ewald uses sources from the 1940s that give France as the origin of the 1918 flu.
In The Great Influenza: The Epic Story of the Deadliest Plague In History John M. Barry discusses the work of Dr. Edwin Johnson, editor of THE JOURNAL OF INFECTIOUS DISEASE, who studied the 1918 soon after it happened and published EPIDEMIC INFLUENZA in 1927.
Dr. Johnson also discards the theory (that some have given) that the 1918 flu originated in China and spread to Europe via imported laborers. Yet he also could not find evidence that it started in Europe.
In Haskell County, Kansas, the winter of 1917-1918 was hard. Many people came down with a flu that was unusually serious. We don't know exactly how many of Haskell County flu victims that winter died, but it was enough to alarm the local doctor. He was so concerned about the number of local and deadly cases of flu that he wrote an alert to the government.
Of course, that didn't stop the government from drafting young men from Haskell County -- who were sent to Camp Funston for training before shipping them off to France.
So it's quite possible that the 1918 flu first infected people in Haskell County, Kansas.
It appears that it did evolve once it was in Europe. The first wave of it hit the soldiers in the spring. It was known as the 3 day flu because large numbers of them caught it, were sick for 3 days and then recovered.
Then it went unnoticed until around September 1918 -- when it spread throughout the world and in 3 months killed many more people than the war itself. From at peace Spain (which was unfairly blamed for it) to the South Pacific to remove Eskimo villages in Alaska.
Perhaps the deadly 1918 flu had its deadly origins for BOTH reasons:
1. It was a mutated avian flu that people did not have any acquired immunity for.
2. Wartime conditions encouraged it to retain and/or increase its lethality, by rewarding it for disabling and killing soldiers so fast and easily.
What does this mean for bird flu today?
We already know it's a mutated avian flu we have no acquired immunity for. It kills over half of its human victims.
There is no major, intense war underway -- but many people in large megacities of the developing world from Rio to Calcutta live in extreme density. One sick person lying in the corner of a corrugated iron hovel could infect many close family members and neighbors. If a pandemic struck, many would be transported to large and overcrowded medical centers.
In such conditions, a bird flu mutation would likely retain or evolve its extreme lethality.
And what if it was "only" as lethal as the virus that caused the 1968 "Hong Kong" virus?
According to the CDC, the 1968 virus would today kill 2 to 7 million people around the world. From 89,000 to 207,000 people just in the U.S. That would not be a worst case scenario but it would certainly cause a lot of fear and concern.
Therefore, bird flu does not have to evolve into a strain as deadly as 1918, to pose a threat to millions of people around the world. Even without a major world war, we are at risk from a bird flu pandemic.
Your first reaction is probably the same as mine was -- what a stupid idea! How can cancer or heart disease be a blessing?
First off, let me say that I do believe that humanity's greatest strength is the ability to persevere in the face of problems and to turn negatives into positives -- lemons into lemonade.
So if you believe, as alternative health advocates do, that you do have some control over your health -- then any disease indicates that you need to make some kind of change in your life.
That may be a change in diet, reducing stress, etc. -- but if you can learn the lesson before the "teacher" disease kills you, you'll be healthier for having had the problem.
As I write, 105 people have died from bird flu from Indonesia to Turkey -- to alert humanity to the danger it's facing. We cannot raise them from the dead, but we can attempt to give meaning to their death by learning how to prevent more, and thereby making bird flu a blessing for survivors and our children.
The first step was taken about 5 months ago by President George W. Bush. As part of his request to Congress for 7 billion dollars to fight bird flu, he wants to advance the technology of making vaccines so that they can be created and manufactured more quickly.
A company in Isreal had already started working on a "generic" flu vaccine. That is, it would train your immune system to target the universal genetic structure of all influenza viruses. They originally planned to do in 5 years. Now they're trying to finish before bird flu goes pandemic.
Those of us who live in the developed world must stop being so complacent.
Because long after bird flu is a boring chapter in history, we will be threatened by new diseases.
Most Americans have heard of Ebola, but are not aware of the many other emerging diseases we have discovered in the past 20 to 30 years. It's a long and scary list.
And although they all seem remote from us, they're all just one international jet flight away. They're no more remote than West Nile fever was before it started killing birds and people in Brooklyn in 1999.
We need to take care of our immune systems.
We need to better track viral infections in people. The developed world needs to make its expertise and resources available, and the developing world needs to make public healthcare and a medical infrastructure a higher priority.
The U.S. Center for Disease Control has done a terrific job at this for many years. It needs to expand its operations, the UN World Health Organization needs to expand and national health systems around the world need to do a better job of tracking and controlling disease threats.
We need to do a much better job of incorporating alternative health methods into standard medical care.
We need to stop counting on Tamiflu and start expanding the use of Vitamin C (especially injected ascorbate for serious illnesses), curcumin, garlic, beta glucans and other supplements from mushrooms . . . for starters.
For poor countries it makes economic sense to make use of regional herbs and supplements over expensive drugs such as Tamiflu.
Also, a massive demand for effective herbs and substances should spur farmers in the developing world to raise those herbs in a sustainable fashion.
This would encourage good use of land and also bring cash income to the poor farmers, everybody else involved in the processing and shipping of the supplements and their communities.
The human race has survived and prospered by learning from its mistakes. A lot of people are going to die for the lessons we learn from the bird flu pandemic -- let's learn and apply as many of those lessons as possible.
Richard Stooker has sinced written about articles on various topics from Bird Flu, Chess and Bird Flu. c 2006 by Richard StookerRichard Stooker is the author of and. Richard Stooker's top article generates over 12100 views. to your Favourites.