The onset of Parkinsons disease is a tragic time for any patient and their families. As a degenerative condition, patients suffering from the condition are faced with no hope of recovery, but rather a slow and wearing process of loss of movement and co-ordination. Most notably, the condition involves the tremor, whereby patients can be seen trembling uncontrollably, as well as loss in speech capabilities and gradually all functionality in its later stages.
Parkinsons disease is a disorder which takes effect on the central nervous system. A movement disorder, Parkinson's can be seen in four major symptoms; namely rigidity of muscles, a tremor of movement, slowing of overall movement (known as bradykinesia) and in certain instances loss of movement altogether. The symptoms gradually become more and more apparent in sufferers, and are progressive, that is patients do not recover, or get better. This degenerative condition is not contagious, nor passed genetically, and very little is known about the causes of most instances of the condition. Having said that, some cases can be explained through extreme drug abuse, cranial damage and other abuses of the body which have been shown to give rise to the condition.
The condition occurs as a result of the loss or destruction of brain cells which produce dopamine, a chemical associated with muscle activity. This chronic condition was first discovered and charted by James Parkinson in 1817, and concerns what he labelled as his patient's 'shaking palsy'.
A disease which has been a mystery to scientists and physicians across the world since its discovery, Parkinsons disease has no known cure, although there are ways to treat it and perhaps stall its development. Additionally, there are a number of support groups for both sufferers and carers, providing some much needed reassurance that all is not lost, and there are still ways to work to help the condition, which can sometimes feel like a distant fantasy.
A particularly crushing aspect of the disease is the impact it can have on a patient's everyday life. The simplest of physical tasks become impossible, leaving the sufferer eventually in need of round the clock care and attention. There is a present no way of knowing who will develop the disease, or to what extent, although reassuringly, scientists the world over are desperately trying to expand their knowledge of the condition and look for other treatments, and possibly even the elusive cure.
Sadly, for patients with Parkinsons today, there is no real way out, and it's best to try and remain as active and involved as possible in the normal daily routine to keep up morale, and keep the patient interested in life. Such a demoralising condition as Parkinsons requires a lot of patience, and it can be particularly hard and frustrating to see a family member descend into such a state. There are however, a variety of ways to significantly reduce the effects of the condition, and it is advisable for anyone worried about themselves or friend or family member to consult their physician for more information on the condition and what can be done to curb its onset.
To date, there is no known cure for Parkinson's, despite the ongoing research efforts of scientists across the world. Having said that, there are a number of treatments available which can substantially relieve the pain many patients feel as a result of the symptoms of the disease. It is not the case that every patient will require medication and drugs to treat their condition, and these will only be administered where the severity of the symptoms has a strong adverse affect on the patient's lifestyle. The course of Parkinsons Medicine offered to a patient will vary with the amount of disruption the symptoms cause, the state of the patient's condition and the severity of the condition within the patient. Even in these cases, it is not always a guarantee that the symptoms will be helped, although these treatments will go someway to making life more comfortable.
The most effective treatment for the symptoms of Parkinson's Disease by a long shot is the drug levodopa. This is derived from a naturally produced chemical in plant matter and animals, and works with the nerve cells to produce the dopamine which has been eroded by the patient's condition, and is thought to be an underlying cause of the disease. The drug allows the majority of patients to extend the period of time in which they can lead their normal lives, effectively stalling the development of their Parkinson's. Unfortunately, this treatment is only really effective in helping rigidity and bradykinesia, and may be of no help to the tremor or balance problems the patient may be experiencing. The drug is so effective, many patients forgot they are suffering from the disease as they continue to lead their lives as normal. However, levodopa is only a short term solution, as it can never replace the nerve cells which have been irretrievably damaged within the brain.
As with most medications, there are a number of side effects with levodopa, including restlessness, low blood pressure and vomiting. In some cases patients may also occasionally feel confused as to their surroundings , although this is a rare occurrence. It is important for physicians and patients to work together to come up with a happy medium between the benefits and side effects when using levodopa.
When combined with the drug tolcapone, Parkinsons medicine significantly reduces the effects of the disease, and helps block the destruction of dopamine which worsens the condition. Having said that, this tends to increase involuntary movement and twitching over a long course of treatment, and is sometimes withdrawn for several days at a time to ensure its continued effectiveness. However, patients should never completely cease treatment with levodopa without their physician's guidance, due to the extreme and serious side effects that can emerge as a result.
Although there is no cure for the disease, Parkinsons medicine can go a long way to suppressing the debilitating and disabling symptoms of the condition, and making life more bearable for the many thousands of sufferers around the world.
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