The present invention is directed to a safe and effective therapy for the treatment of pain associated surgical incisions, wounds, cuts and abrasions. The present invention relates to a pharmaceutical composition comprising a combination of a guanylate cyclase inhibitor and a topical anesthetic or a combination of a redox dye and a topical anesthetic. The compound and treatment may be used to relieve pain resulting from surgical procedures, especially anal surgery.
WO9937223
A modality of twitch obtaining intramuscular stimulation (IMS) pain relief therapy employs an EMG needle (13) having a TEFLON coated shaft, and exposed conductive tip (17) to apply micro-electrical stimulation locally, and focally to muscle motor end plate zones or regions of adjacent motor end plate zones. The electrical stimulation facilitates the elicitation of strong twitch responses from muscle fibers associated with the stimulated motor end plates, generally without requiring physical needle manipulation following the initial pin insertion. Less skill is required to effectively elicit pain relieving twitch responses, thus facilitating training of medical personnel to carry the procedure. Rapid movement between multiple treatment sites is possible allowing treatment of a larger number of afflicted muscles, and muscle areas in a single treatment session. The strength, the number of twitches obtained at the treatment sites can provide substantial relief from regional, and diffuse myo-facial pain of radiculopathic origin. In addition, since physical manipulation of the pin is generally unnecessary, patients experience less pain, less discomfort during the procedure, and the risk of repetitive stress injury to the therapist is reduced
WO9851225
Intramuscular stimulation (IMS) pain relief therapy is facilitated by a hand held tool (1) which once positioned against a patient's skin can be controlled to automatically advance a needle (11) to penetrate the patient's flesh, reciprocate the needle (11) within the patient's flesh a predetermined number of times through a predetermined stroke, and retract the needle (11). A tubular guide member (13) is provided at its distal end with a skin contact member (15) forming a constricted orifice closely matching the diameter of the needle (11). The orifice allows substantially free passage of the needle (11) therethrough, and at the same time prevents bowing of the needle (11) as it is advanced, which is a primary source of patient pain. Automation and control of the needle penetration; reciprocation and retraction sequence reduces the amount of manual, and mental effort required on the part of the treating physician, thereby allowing physicians to perform IMS procedures more consistently effectively and efficiently. This leads to better results (increased pain relief); decreased procedure induced patient pain and tissue trauma; and reduced risk of repetitive strain injury to the treating physician.
WO9840070
Methods and compositions for treating pain at a specific site with an effective concentration of capsaicin or analogues thereof are described. The methods involve providing anesthesia to the site where the capsaicin or analogues thereof is to be administrered, and then administering an effective concentration of capsaicin to the joint. The anesthesia can be provided directly to the site, or at remote site that causes anesthesia at the site where the capsaicin is to be administered. For example, epidural regional anesthesia can be provided to patients to which the capsaicin is to be administered at a site located from the waist down. By pretreating the site with the anesthetic, a significantly higher concentration of capsaicin can be used. Effective concentrations of capsaicin or analogues thereof range from between 0.01 and 10 % by weight, preferably between 1 and 7.5 % by weight, and more preferably, about 5 % by weight. This provides for greater and more prolonged pain relief, for periods of time ranging from one week to several weeks. In some cases the pain relief may be more sustained because the disease that underlies the pain may improve due to a variety of factors including enhancement of physical therapy due to less pain in the soft tissues which may foster enhanced mobilization of soft tissues, tendons, and joints.
US2003105417
PAIN AWAY consists of two handgrips (F) on either side of a treatment core (R). This treatment core (R) has a pair of permanent belts (L) mounted on wheels (C) for pressure treatment of the muscles beside the spine, to relieve back pain and produce relaxation. A detachable belt (M) is used for cellulite treatment. The device vibrates as desired. Since this is the first device based on the acupressure method of back pain relief it is unique in concept. Drake's search of existing patents as provided by the PTDL in Dallas, Tex. #606/204 revealed nothing like PAIN AWAY. Specific features that make it unique are: (1) the fact that it rolls up and down the back; and other parts of the body, eliminating the use of creams or abrasive rubbing motions; (2) the pyramids on the belts need not ever touch the skin itself thereby lessening the chance of transmittal of any infections from one person to another (if the device is used in a commercial manner such as hospital therapy); (3) the fact that the spinal gap spacer (and vibrator housing) (B) makes it ideal for the treatment of spinal pain associated with muscle tension; (4) the fact that the pyramids (S) on the belts (L, M) are rubber will prevent injury: (5) the fact that the simplicity of the use of PAIN AWAY makes it easy for a non-professional to use easily: (6) the fact that it is a cellulite treatment method that does not require lotions and cremes.
US2001037076
A temperature compression treatment garment for providing therapy to the chest and/or breasts for relief of pain and discomfort, comprising a band which is wrapped around the upper torso at the level of the chest and/or breasts and which applies compression variably and independently horizontally across the chest. The band has front and back shoulder straps which connect to apply compression variably and independently vertically across the chest. The band also has a frontal flap which forms a pocket for the insertion of a thermal device, such as a gel-pack, to heat or cool the chest and/or breasts of a user.
US6546290
An apparatus for providing therapeutic electrical signals has a plurality of sets of electrodes, each set of electrodes comprising at least two electrodes for applying the therapeutic electrical signal to a user. A switch selectively switches the therapeutic electrical signal to each of the electrodes in a predetermined pattern. The electrodes are arranged on a flexible platform which can substantially conform to surfaces of the user. The therapeutic electrical signal can be applied to the sets of electrodes in any predetermined pattern, including a predetermined pattern that sequentially sends the therapeutic electrical signal in a first direction to each set of electrodes. Preferably, the sets of electrodes comprise at least three electrodes arranged in a substantially chevron pattern with a center electrode having the opposite potential to the side electrode. The therapeutic electrical signal is generated by a signal generator. The signal generator generates different types of therapeutic electrical signals by applying a base wave with a frequency of about 150 KHz to 180 KHz at different frequencies between about 2 to 100 times in a second. The switch selectively switches the different types of therapeutic electrical signals in the predetermined pattern. The signal generator can decrease the therapeutic electrical signals from its maximum to its minimum within about 0.1 to 0.01 microseconds. The therapeutic electrical signal is switched to a next set of electrodes within about 0.5 to 2 seconds. The apparatus and method can be used in a variety of treatments, including relief of pain, relief of stress, electronic acupuncture and transcutaneous electrical nerve stimulation.