There is such a thing as acetylcholinesterase in our body. This is one of the more unloved substances which our body produces to efficiently destroy other molecules. The thing about this enzyme is that it specifically targets the molecule, acetylcholine, which is actually a versatile neurostransmitter that acts as messenger for the central and peripheral nervous systems. Having said that, acetylcholine molecule therefore serves as mediator for a host of vital functions, including many related to cognition and memory.
So why then, did Mother Nature create such an enzyme that can cut down the number of sanity-preserving acetylcholine in half? Because, as we all say, too much of a good thing can't be good. Think too much glucose can result in diabetes. And too much television can warp your brain. That sort of thing.
The human body, like our society, is comprised of all sorts of checks and balances to keep everything in order. So we have our "good" molecules here and "bad" molecules there. The "bad" molecules will destroy the "good" molecules while other "bad" molecules will destroy the "bad" molecules that destroyed the "good" molecules and this just goes on and on. Like a good Chinese box puzzle.
Huperzine A is badder than bad
Now there is a molecule that keeps the "bad" molecule acetylcholinesterase at bay. This molecule is called Huperzine A.
Huperzine A is actually an alkaloid found in the Chinese herb Huperzia serrata. Huperzine A specifically targets molecules that destroy the memory-enhancing neurotransmitter, acetylcholine. Because of this function, Huperzine A is therefore effective in improving cognitive and memory abilities in humans, including those with Alzheimer's disease (Most Alzheimer's cases exhibit a shortage of acetylcholine and an abundance of acetylcholinesterase).
In China, Huperzine A is used to treat patients with Alzheimer's disease and myasthenia gravis. Scientists have studied the effects of this alkaloid substance on the mental functions of elderly Alzheimer's patients with successful results.
In a strictly controlled experiment rigorously designed by experts, patients with ages ranging from 52 to 80 were used as subjects. All 60 patients have one or more impaired faculties as a result of the action of acetylcholinesterase. Two groups were treated using 200 mg of synthetic Huperzine A daily in either capsules or tablets while the other group was given placebo. The experiment lasted for 60 days and afterwards, during the evaluation using an array of both psychological and physiological tests, improvement rates in both groups ranged from 43% to 70%. No statistical evidence was found that significantly marked the difference between the capsule group and the tablet group. This led the scientists to conclude that Huperzine A may have very positive effects on the cognitive aspects of the human brain.
Huperzine A is good not just for the old, geriatric people, but for the young as well. In another study designed to examine the effects of Huperzine A on the mental functions of adolescents, Chinese researchers found that the compound can enhance memory and learning in young adults.
Buying Information
Based on the results of the study, Huperzine A is superior to the drugs tacrine and donepezil, which are both acetylcholinesterase inhibitors widely prescribed for Alzheimer's disease. There is no doubt that these two drugs are effective, however, Huperzine A is a naturally occurring substance and as everyone is wont to agree, natural substances are far better compared to synthetic ones.
Head First
Good health starts with your brain. It's one of the body's most vital organs and it needs care and maintenance.
Ongoing mental and physical exercise
Exercise keeps the brain healthy. Either use it or lose it. Regular physical activity increases the blood flow to the brain and provides the nutrients necessary to render its tissues resistant to Alzheimer's. Exercise also increases the number of connections among the millions of brain cells needed for normal mental function. Get into the habit of walking for thirty or sixty minutes a day as briskly as possible. Stair climbing is particularly effective, so take the steps when going up or down one or two flights and leave the elevators and escalators to the kids.
Education
Several population studies have shown that the more schooling you have, the greater are your chances against Alzheimer's. That may be because the educated are more likely to eat more nutritiously and receive better medical care throughout their lives. However, like physical exercise, ongoing intellectual challenges stimulate the formation of nerve connections. Even if you are destined to develop Alzheimer's, the more neutrons you develop when you are young, the more you can afford to lose before symptoms set in.
Many retired seniors sign up for classes in accounting, law, art, music, economics, or whatever else interests them to stay mentally active, and not necessarily to start a second career. The longer you continue your education at any age, or keep your mind busy in some other way, the more likely your neurons are to connect with each other later on.
Reduce stress
Chronic stress (as well as anxiety and depression) raises your body's production of the adrenal hormone cortisol. High levels of cortisol have been shown to lead to memory impairment and atrophy of memory centers in the brain. Stress reduction techniques such as exercise, meditation, yoga, Tai Chi and biofeedback may help to combat chronic stress, anxiety and depression.
Diet
Eat as little animal fat as possible to reduce your vulnerability to Alzheimer's. The incidence of Alzheimer's in different countries correlates with the consumption of total fat. Fro example, in the United States, 5 percent of all persons over the age of sixty-five have the disease, while in China and Nigeria, where the fat intake is much lower, the incidence is only 1 percent. Japanese who move to America and double the amount of fat in their diet have twice the incidence of Alzheimer's than do those who do not emigrate and presumably maintain their old eating habits.
Nicotine
Nicotine is a prime example of how new research data can supersede and negate previously acquired information. We used to believe that smokers were less likely than non-smokers to develop Alzheimer's. But the anti-tobacco community is now breathing easier because more recent studies indicate that smoking doubles the risk of getting Alzheimer's.
Vitamin E
Hardly a day does by without some favorable report about vitamin E. I can't think of any downside of this vitamin, with the possible exception of its raising blood pressure and causing some extra beats in some people. Vitamin E increases fertility in rats; it's good for the heart; and many doctors prescribe it for the treatment of vascular disease, particularly for narrowing the arteries in the legs. Now comes word that vitamin E may also delay the onset of Alzheimer's, presumably by virtue of its antioxidant properties. Antioxidants, of which there are many, are said to neutralize the harmful effects of free radicals, the byproducts of bodily process that involve oxygen. These radicals carry an extra electron that can damage the protein in the brain and other organs and accelerate the aging process. The body's own antioxidant normally neutralizes these free radicals, but this defense can be enhanced by supplemental vitamin E.
Hold off on heavy metals
Heavy metals such as mercury and lead are known to cause brain injury that may not be reversible. Sources of heavy metals include large fish (such as swordfish, tuna steaks, tilefish, king mackerel, shark, halibut and mahi-mahi), which are high in mercury and ?silver? dental fillings. Lead exposure may occur from old paint and some calcium supplements, which have recently found to be contaminated with lead.
Along the way, neurologists have discovered that the brain is much more adaptable as it ages than they realized. They have determined that the so-called plasticity of the brain, which allows the formation of new neurons as well as new connections between those neurons, can last a lifetime. "As far as our brains are concerned, learning something new or even retrieving something from memory is a plasticity response," says Molly Wagster of the National Institute on Aging
Both Nazima Golamaully & Fred are contributors for EditorialToday. The above articles have been edited for relevancy and timeliness. All write-ups, reviews, tips and guides published by EditorialToday.com and its partners or affiliates are for informational purposes only. They should not be used for any legal or any other type of advice. We do not endorse any author, contributor, writer or article posted by our team.
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