The research supports that Vinpocetine may guard against such developments by increasing blood circulation in the brain. This is particularly true for people already experiencing a degree of age-related cognitive impairment.

Vinpocetine is a derivative of an extract taken from the periwinkle plant, an evergreen undershrub. The shrub is native to Europe, where it has been under examination since the 1950s for combating stroke and age-related decline in brain function. Only recently has Vinpocetine become available in the United States, and not as a prescription drug like in Europe, but as an over-the-counter dietary supplement.

Vinpocetine also enhances the brain's use of oxygen by increasing the amount of ATP (adenosine triphosphate, the body's cellular fuel). People suffering from dementia caused by numerous tiny strokes appear to benefit from an increased oxygen-rich brain environment. This condition can cause memory problems that closely resemble those of Alzheimer's disease. Vinpocetine may be able to protect the brain from damage caused by strokes.

Extensively studied in Europe, Vinpocetine has also been used to treat symptoms of acute stroke, motor disorders, and dizziness. Some studies indicate a possible value for improving visual acuity and hearing as well. Even otherwise healthy people experienced improved short-term memory with Vinpocetine.

In addition, research indicates that Vinpocetine may also:

?Increase ATP (energy) levels in the brain
?Enhance use of glucose by brain cells
?Stop or prevent blood from becoming sticky
?Enhance memory and learning
?Increase levels of serotonin and other neurotransmitters
?Increase the tolerance of the brain to lack of oxygen supply to the brain
?Enhance cerebral metabolism
?Improve vision
?Help with depression/mood changes/sleep disorders
?Aid with tinnitus and other causes of hearing impairment

The long term benefits of using Vinpocetine as a nutritional supplement may outweigh the short term benefits, by enhancing the supply of oxygen and nutrients to one's brain over several regenerative cycles.

Vinpocetine is nontoxic even in doses several times higher than those used normally (Vinpocetine is 50 times less toxic than a cup of coffee at recommended doses) and has a low risk of side effects especially when taken with food. Vinpocetine supplements should be avoided by women who are pregnant or who are nursing, and by those with a history of hypersensitivity or allergic reactions. Also, prolonged use of Vinpocetine may lead to slight reductions in blood pressure. Reported adverse reactions include dry mouth, nausea, drowsiness, facial flushing, dizziness, transient hypotension and tachycardia, headache and insomnia.

Overall Vinpocetine appears to be a useful supplement for promoting the proper cognitive functioning of the brain ? one that may increase in use and popularity as its attributes are more widely recognized by our aging American public.