Researchers from Massachuttes General Hospital believe that 45 150 men who did not have gout in the following years they have developed it. The most common inflammatory arthritis for men is the gout. The deposit from the joints is caused by the uric acid crystals. The body's immune system is stimulated by the build up of these crystals.



Swollen and very painful joints are the symptoms of people with gout. The raising of the gout is due to the following factors: changes in lifestyle like being less active, changes in diet like drinking alcohol and eating red meat, changes in social behavior like the increased use of labour-saving devices.

It is generally known that gout does have a genetic basis. A theory saying that drinking alcohol raises the risk of developing gout it's true. From this point of view the alcohol dose play an important role. The deposit of uric acid in the joints and drinking alcohol, due to the existence gout develop the levels of uric acid in the body.From this one results the risk up in the joints.

The build up in the body is influenced by the two ways of the uric acid: less removal of uric acid of the body through the kidneys and more production of uric acid in the body. Uric acid removal and production are affected: the case when alcohol is converted to lactic acid, it reduces the amount of uric acid that is removed from the body through the kidneys. The lactic acid interacts with the uric acid for removal from the kidneys into the urine.

Increased level of ethanol in the body increases the body production by increasing the amount of ATP is converted to AMP - a precursor of uric acid. There are some portions to measure the alcohol consumption amount the men who studied: 12oz (355ml) bottle or can of beer which contains 12.8g of ethanol, 4oz (118ml) glass of wine which contains 14.0g of ethanol, 1 shot (44ml) of spirits which contains 14.0g of ethanol.

Different studies has shown that the risk of gout was significantly raised with alcohol in take as low as 10.0-14.9 g per day and on the other hand for the men who consumed 50g or more per day the risk of gout was 2.5 times higher. Compared with drink no alcohol:10-15 g per day raising the risk with 30 percent, 15-30g per day raising the risk with 50 percent, 30-50 g raising the risk with 100 percent and more then 50 g raising the risk with 150 percent.

The developed of gout with increasing alcohol was not the same for each type of drink for example 2 or more bottles per day raise the risk of the gout by 2.5 times compared with no beer intake, 2 shots of spirits per day develop the risk of gout by 1.6 times in comparison with no spirit intake and 2 glasses of wine are considered as inoffensive. The risk perceiving of beer is higher than that for spirits because spirits contain more alcohol than beer. Thus, researches considered that there might be another non alcoholic ingredient in beer that was helping to increase the risk of gout.

The researchers also pointed out that beer is the only alcoholic drink which contains chemicals known as purines. So this chemicals play an important role for gout. The researchers argued that purines could contribute to the increase risk associated with drinking beer. But this argument has been changed by other doctors who pointed out that the evidence for purines playing a major role in gout is not conclusive. They were referring to a study of Taiwanese vegetarians who ate a diet that is high in purines. These people had reduced the risk of developing gout. The type of drink could have a direct effect in the risk in developing gout, do to the non alcoholic ingredients in the drink.

This has not been proven and other doctors think that other factors are causing the difference in risk. The doctors who disagree with the idea that the drinks themselves have different risks suggested the fact that the type of drink choose to consume reflects someone's lifestyle. People who drink beer may choose to exercises less or eat more risky foods than people who drink wine - the presence of a difference in risk between types of drink. The lifestyle choice is responsible for increasing the risk of gout. It is impossible to say that wine is a "safe" option. It is known that 21 units a week for adult males and 14 units a week for females are recommended. It is very important for people who have gout to keep a proper diet and avoid drinking alcohol in a big amount.

For reducing health risks for drinking no more than 3-4 units per day for men and no more than 2-3 units day for women are given as an advice by the doctor. The ideal recipe will be the following: half a pint of beer, cider or larger, a 25 ml measure of spirit like votka, whisky or gin, a 50 ml measure of fortified wine like port or sherry and a small (125 ml) glass of wine.