The Hebrew University's Center for Nanoscience and Nanotechnology takes an interdisciplinary approach to meet the challenges of this new and exciting field. Bringing together researchers from a number of departments, the Center begins with a unit for nanoscopic characterization to ?see,? identify, and describe the nanometric structure the researchers have created. The Center intends to construct a unit for nanofabrication where nanometric structures will be built.
Materials that have been shrunk to a nanoscale often display very different properties from the corresponding materials in a normal macroscale, and this enables unique applications. For example, opaque substances can become transparent, inert materials sometimes develop into catalysts or suddenly become combustible, solids might turn into liquids at room temperature, and insulators like silicon can be transformed into conductors. Much of the current allure of nanotechnology has been generated from the unique phenomena that certain materials exhibit at the nanoscale.
The techniques developed in the last few years have made it possible to assemble tiny molecules into almost any structure. These methods are now being used today to create an amazing variety of useful chemicals, like pharmaceuticals and commercial polymers.
Wide-Ranging Nano-Applications
The Hebrew University's unique interdisciplinary approach leads to research that has applications in a number of industries:
? Semiconductors. Work is being carried out on nanostructured semiconductors, superconductors, and composite materials.
? Medicine. Systems are under development that trap single cells to study and quantify them down to the molecular level.
? Telecommunications. Research is being carried out in nanophotonics and on optofluidic components and devices to provide smaller, faster and more versatile options for telecomunication.
Through the efforts and resources of Yissum, Hebrew University's active Technology Transfer Services organization, a number of these projects in nanotechnology are already on the path toward commercial success. A composite thin film composed of sol-gels with metals and nano-particles is at a stage where it is ready for testing as an anti-corrosion coating for the automotive industry and a non-viral delivery method for gene therapy is ready for testing for various applications.
Selected Researchers
Almost 30 researchers currently lead and develop cutting-edge projects for the Center. Cooperation between these multidisciplinary scientists enables development of a true understanding of the environment in which the 1-100 nanometer objects created by the researchers exist and operate.
The Center's researchers are drawn from across the scientific spectrum at this Technology Transfer University.
? Department of physical chemistry: Danny Porath and Uri Banin are studying DNA nanoelectronics and nanoparticles in a variety of applications, respectively.
? Department of inorganic chemistry: Daniel Mandler and Shlomo Yitzchaik are involved in the production of sol-gel and ultra-thin films.
? Faculty of medicine: Dan Gazit is working on nanotechnology-based skeletal tissue engineering and gene therapy.
Marketing and legal professionals from Yissum work together with all of the Center's researchers to ?transfer? the technology from the laboratory to the market.
It appears that as our view of the world becomes more and more global, science needs to focus on smaller and smaller matters to prepare us for the future.
American Friends Hebrew University
Novel drug delivery solutions come about as the result of research into many different Technology Transfer Services areas and fields, including liposomes, polymers, controlled release and encapsulation technologies, and microparticulate and nanoparticulate targeting systems. At the Hebrew University, research into groundbreaking drug delivery systems is underway by some of the world's acknowledged experts in a number of different fields.
In the School of Pharmacy
• Professor Abraham Domb is an expert in degradable polymers, nanoparticles, and biomaterials
• Professor Elka Touitou leads research in the enhanced delivery of peptides and other drugs through biological membranes
• Professor Simon Benita is a specialist in microparticulate and nanoparticulate targetable drug delivery systems.
At the Casali Institute of Applied Chemistry
• Professor Shlomo Magdassi is an expert in formulation chemistry, nanotechnology, surfactants, dispersion systems, microparticles, and microcapsules.
In the Department of Organic Chemistry
• Professor Chaim Gilon specializes in medicinal chemistry and synthetic chemistry
And at the Institute of Biochemistry, Food Science and Nutrition of the Faculty of Agricultural, Food and Environmental Quality Sciences
• Professor Amos Nussinovitch specializes in the theoretical and practical aspects of hydrocolloids, including: coating of cells, hydrocolloid glues, hydrocolloid cellular solids and water-soluble polymer uses.
Drug Delivery Successes
The Hebrew University has achieved several significant successes in this truly cutting-edge field.
• Doxil (Doxorubicin HCI liposome injection), Alza's lead product for oncology, was developed by Professor Yechezkel Barenholz of the Faculty of Medicine. It resulted in $375 million in sales in 2006.
• Professor Barenholz also co-founded NasVax Ltd. to develop intranasal delivery systems based on platform technology developed together with Professor Eli Kedar of the Hadassah Medical School. The company's intranasal delivery system for the influenza vaccine sped from bench to clinical trials in less than 18 months. Within one year of operations, NasVax completed two private investment rounds and had a successful IPO on the Tel Aviv Stock Exchange (TASE). The company is traded under the symbol NSVX.
• Novagali Ltd. was founded to develop solutions for ophthalmology. Based on technology developed by Professor Simon Benita, Novagali's pipeline includes major products at various stages of development for dry eye, allergy, glaucoma, retinopathies, and more. To date, Novagali has succeeded in raising €44 million in investment funding.
Outstanding New Technologies
Among the drug delivery technologies Yissum has available for Technology Transfer Opportunities and commercialization are
• A method for preparing non-toxic, biodegradable polymers that can be designed to exhibit pre-determined characteristics and functionality
• A delivery carrier and new combination of FDA-approved drugs for intranasal drug delivery
• A sustained release delivery system for antioxidants
• Highly adhesive patches derived from a tree gum exudate for transdermal and topical drug delivery
• A simple, flexible encapsulation method for loading liposomes with biologically active materials
Yissum is the technology transfer company of the Hebrew University of Jerusalem. Over the past 40 years, Yissum has granted more than 400 technology licenses and is responsible for commercializing successful products that generate nearly $1 billion in worldwide sales every year.
Both Chris Beckley & Mary Waltrip are contributors for EditorialToday. The above articles have been edited for relevancy and timeliness. All write-ups, reviews, tips and guides published by EditorialToday.com and its partners or affiliates are for informational purposes only. They should not be used for any legal or any other type of advice. We do not endorse any author, contributor, writer or article posted by our team.
Chris Beckley has sinced written about articles on various topics from University of, Web Development. Yissum is the . Over the past 40 years,. Chris Beckley's top article generates over 480 views. to your Favourites.
Mary Waltrip has sinced written about articles on various topics from University of, Alcohol Treatment and Addictions. is the of the Hebrew University of Jerusalem.. Mary Waltrip's top article generates over 9900 views. to your Favourites.
Best Adult Affiliate Program The system will check the latest click from the same IP address and browser information as sale within 3 years told by Felix the affiliate manager of sunrxpartners.