In the respiratory system the thin mucus lining becomes thick and sticky. In cystic fibrosis management, the primary treatment of the system is to thin or clear this mucus. Bronco dilators like albuterol are used to clear the clogged airways. Mucus thinning drugs delivered by aerosol, like pulmozyme, are helpful. The most effective way of clearing this mucus is by mechanically dislodging it. Clapping on the chest and back, with the head tilted on the edge of a table, is quite effective. There is an electrical clapper that does the job safely. There is an electrical inflatable vest that vibrates and dislodges the mucus. Infection is an ever-present risk with cystic fibrosis patients. Regular shots for pneumonia and influenza are very important. Bacterial infection is fought with newer antibiotics like TOBY, which delivers the medicine directly into airways with aerosols.
Because of the blocked ducts of the pancreas and liver, the enzymes and bile do not reach the intestine. Though the patient eats normally or even in excess, the fats and proteins are not digested. So the cystic fibrosis patient needs to have the enzymes supplemented with oral pancreatic enzymes. There is also the need to take vitamins, especially the fat-soluble ones. If lung function is completely damaged, the only alternative would be lung transplantation. This would involve many factors, like the availability of a donor and the patient’s present health, prior to undergoing major surgery.
The Cystic Fibrosis Foundation has 115 centers all over America, and provides guidelines and advice. They support many studies to find gene therapy to cure cystic fibrosis. The target is to add normal genes to the cells of the airways to prevent further damage. Biotech laboratories produce healthy genes, which need to be delivered to the appropriate cells. These vectors, or delivery systems, are the key areas of research to combat cystic fibrosis. One method that is actively pursued is to modify the common cold virus to carry the healthy genes into the correct cells. On another track, the DNA molecules are compacted to their minimum size and delivered directly to the relevant cells without the need for a carrier such as a virus. This technology is called PLAS min.
As this gene therapy experiments are at an advanced stage, the cystic fibrosis sufferers can hope for a permanent cure in the near future.
Cystic Fibrosis And Treatment
Cystic Fibrosis is a genetic disease that seriously affects lungs, liver, intestines and pancreas. Technically speaking, Cystic Fibrosis shortly called as CF in medical terms is a genetic disorder where the secretory glands in the body are not normal functional. It's a condition which is mostly observed in the childhood of patients, sometimes as early as in their births. Mucus, sweat and other bodily secretions are affected by Cystic Fibrosis and as a result they cause serious health problems for the patients.
Mucus generally is thin and slippery substance around the lungs which helps to filter, and to absorb dust particles and other micro organisms thus prevents them entering into lungs. For a Cystic Fibrosis patient, the mucus generally would be thick and this is what causes breathing problems to the patient. The digestive secretions too are abnormal and don't help food to digest and vitamins to absorb properly. This is why Cystic Fibrosis affected people are mostly underweight and have a poor growth ratio.
Causes of Cystic Fibrosis
The single main cause of the Cystic Fibrosis is parental inheritance. Like most of the genetic disorders, the CTFR (Cystic Fibrosis Transmembrane Conductance Regulator), a defect gene will be inherited by the child from their parents who suffer from Cystic Fibrosis. This CTFR controls the water and salt content in the body cells. So the defected CTFR gene results in formation thick mucus and releasing excess content of salt in sweat.
Symptoms of Cystic Fibrosis
There are far too many symptoms that circulate around Cystic Fibrosis thus making it difficult to judge the disease by symptoms alone. And the symptoms too vary from person to person depending upon the disease condition of the patient. However there are some basic symptoms of Cystic Fibrosis like symptoms related to respiratory and digestive systems. The first and foremost symptom is thick mucus around lungs and airways which always causes lung and chest infections.
Chronic cough, pneumonia, abnormal foul smell of bowls, mucus in bowls, improper bowl movements, unusual weight loss, poor growth, abdominal pains, dehydration and excess loss of salt in sweat are the common symptoms of Cystic Fibrosis.
Available Treatments
At present, there are no major treatments available for Cystic Fibrosis to cure it in a single sitting or surgery. The approached gene therapy at early stages of disease can bring a change in defective CTFR gene. But for the doctor, the most important thing is to minimize the symptoms of disease thus helping patient to lead a painless life.
The most practiced treatment these days is anti biotic therapy which reduces the disease effects of CF affected patients and thus increasing the average life span of patients drastically. The bronchodilators, mucolytics and decongestants are some of medical practices that ease the breathing system and reduce lung infections in patient.
A specific low fat diet plan can help out solving the digestive problems that naturally come along with Cystic Fibrosis. There are also some prescribed exercises and physical activities that can ease thick mucus and helps to drain quickly. A proper maintenance can help CF patients to live life normally without many hassles.
Both Kent Pinkerton & James S. Pendergraft are contributors for EditorialToday. The above articles have been edited for relevancy and timeliness. All write-ups, reviews, tips and guides published by EditorialToday.com and its partners or affiliates are for informational purposes only. They should not be used for any legal or any other type of advice. We do not endorse any author, contributor, writer or article posted by our team.
Kent Pinkerton has sinced written about articles on various topics from Careers and Job Hunting, Family Concerns and Cyst. provides detailed information on Cystic Fibrosis, Cystic Fibrosis Symptoms, Causes Of Cystic Fibrosis, Cystic Fibrosis Treatments and more.. Kent Pinkerton's top article generates over 18100 views. to your Favourites.
James S. Pendergraft has sinced written about articles on various topics from Health, Alternative Medicine and Bacterial Vaginosis. Dr. James S. Pendergraft opened the Orlando Women's Center in March 1996.. James S. Pendergraft's top article generates over 12100 views. to your Favourites.
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