Cialis is effective and safe in any etiology and severity of erectile dysfunction. One of the advantages of Cialis is its duration; the ability to erect in response to sexual arousal persists to 36 hours, so there is no need to plan the time of sexual proximity. Cialis restores natural spontaneity of sexual life.

Cialis belongs to the class of enzyme inhibitors phosphodiesterase-5. Its effect is based on a selective and effective blockade of phosphodiesterase-5 that promotes to relax the cells of plain muscles and increases blood flow to the penis. Cialis treats erectile dysfunction by increasing blood inflow to penis when having sexual initiation.

Cialis is intended for the treatment of erectile dysfunction of any degree of seriousness. Cialis is easy to apply. Its recommended dose is 20 mg before the alleged sexual activity, regardless of the collateral meal or alcohol.

At this time, Cialis is the only phosphodiesterase-5 inhibitor, the effect of which persists more than a day- up to 36 hours. It is important to note that erection occurs only with sexual initiation. This will allow the couples not to plan their sexual relationships and not to abandon the normal rhythm of life. Having a preparation in morning, you can take advantage of its effect in the evening. Maximum recommended frequency of reception is once a day.

Cialis has already proven itself well in Europe, Australia and New Zealand. The first countries where the drug appeared were Britain, Denmark, Finland, Sweden and Germany.

Currently, more than 4000 men have participated in more than 60 clinical studies which had proved the effectiveness and safety of the drugs. Cialis improved erectile function with 81% of men and showed good tolerance.

Cialis positively affects the following manifestations and consequences of erectile dysfunction:

- erection in general;

- the ability to have erection sufficient for sexual intercourse;

- the ability to support erection when sexual intercourse;

- obtaining satisfaction from sex;

- positive emotions;

- confidence in the ability to achieve and maintain erection;

- satisfaction of sex partner.

- because Cialis has a prolonged effect, men can now not to think constantly about the admission of the drug.

The product has no effect in the absence of sexual stimulation. Cialis is not intended to apply to women. For healthy individuals Cialis isn't changing blood pressure and heart rates. The use of food and alcohol does not affect the speed and duration of Cialis that allows men not to change their habits and addictions.

Cialis has high efficiency, which not only improves erection, but also helps the patient to regain naturalness of sexual relations. Cialis is reliable, efficient, easy to use and safe, it restores a normal sex life for patients suffering from erectile dysfunction, freeing them from the constant thoughts about treatment.

The patients receiving any form of organic nitrates should not take Cialis, or any other PDE-5 inhibitor. This combination can cause a dangerous drop in blood pressure. If the patient complained of chest pain or other symptoms related to cardiopulmonary resuscitation during sexual intercourse, he must immediately appeal to a doctor. In clinical trials the most frequent side effects ware headache, dyspepsia, back pain, aching muscles and the blood flash to face. Side effects are usually weak or moderate, pass quickly, and the frequency decreases with constant use of the drug. In clinical studies, most men did not suffer from serious side-effects, which forced them to stop taking Cialis.

Patients receiving any form of nitrates should not take Cialis. If the patient takes Cialis, while taking any drug on the basis of nitrates, blood pressure can drop to dangerous level. Many medicines which are prescribed for the treatment of sternum pain caused by heart disease contain nitrates. These drugs include nitroglycerine (aerosols, ointments, plaster or pastes and tablets) or isosorbide dinitrate and mononitrate. Some light drugs such as amyl nitrate also contain nitrates. Spesified list is far from complete, so it is important to know if you accept nitrates or drugs containing them. Because there are no data of controlled clinical studies on safety and efficacy of the drug, Cialis in the following groups of patients should be prescribed very attentively:

- patients with severe renal insufficiency;

- patients with severe liver failure.

Cialis has contraindications in such cases:

- the set of heightened sensitivity to tadalafil or to any substance included in the composition of the drug;

- in the case of reception the preparations containing any organic nitrates;

- applying for persons under 18 years of age.

The most frequently observed side effects were headache and dyspepsia (11% cases and 7%, respectively). Unwanted events associated with taking tadalafil are usually small or medium, pass quickly and reduce while continuing taking the drug. Another undesirable effects were back pain, myalgia, stuffiness in nose and blood flash to face. Seldom there were chemosis, ophthalmic pain, hyperemia of conjunctive and dizziness.

Sexual activity has a potential risk for patients with cardiovascular disease. Therefore, the treatment of erectile dysfunction, including the use of Cialis, should not be prescribed for men with heart disease, in which sexual activity is not recommended. The potential risk of complications with sexual activity of the patients with cardiovascular disease should be taken into account:

- myocardial infarction in the past 90 days;

- unstable stenocardia or stenocardia arising during sexual intercourse;

- heart failure of class 2 and higher by NYHA, evolved during the last 6 months;

- violations of heart rhythms, hypotension or arterial hypertension;

- old stroke during the last six months.