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Enlargement Of The Prostate

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If the disease is neglected, there will be a marked retention of urine, and the back pressure of the urine increases more and more, resulting in dilation of the ureters (called hydroureters), as well as of the kidneys (called hydronephrosis). An enormous growth of bacteria will occur in the entire urinary tract, leading to pus formation, and the kidneys will be grossly infected. This is called pyonephrosis ('pyo' means pus, 'nephros' means kidney). Patients can hardly pass urine, and repeated catheterization may be required. Hence, the value of early diagnosis and treatment may be stressed again.



How to establish the diagnosis of benign enlargement of the prostate?

A simple DRE (digital-rectal examination) carried out by a physician/ surgeon is highly useful. In this procedure, a gloved, lubricated index finger is pushed through the anus, after making the patient assume a knee-elbow position, Prior to this examination, the patient is asked to pass urine as much as possible. The finger in the anal canal then feels the prostate. First of all, it must be checked carefully that there is no nodule, or some other feature suggestive of cancer of the prostate. With this examination, one gets a fairly good idea about the extent of enlargement of the prostate, and it should be carried out in all cases systematically.

The above examination should be followed by an ultrasonographic examination of the prostate. It is a very useful as well as accurate test. It gives all the details of the prostate, like its exact size, weight, any nodule suggestive of cancer, or any stone in the prostate, including the exact amount of the residual urine. If need be, a more specialized ultrasonography (trans-rectal prostate sonography), in which a special probe is used, can be carried out to rule out any doubt regarding cancer of the prostate, in selected cases.

If in a case of enlarged prostate, there is an associated infection of the urinary tract/renal failure / renal insufficiency, more tests will be required.

Treatment of a benign enlargement of the prostate

It should be stressed that an enlarged prostate alone is not sufficient indication for an operation. The patient must have symptoms, and, above all, a significant quantity of 'residual urine', for considering medicinal/operative treatment.

In early cases, some of the drugs available may be tried. However, in cases where symptoms are markedly distressing to. the patient, and the 'residual urine' is highly significant, the operation should not be delayed. Above all, what is needed is the quick removal of any obstruction from the passage of the urinary tract, for the prevention of UTI.

If the patient takes care of his enlarged prostate, he can be easily operated on by a transurethral resection of the prostate (TURP), in which no surgical incision is required. The instrument is simply passed through the penis, of course, under anaesthesia, which cuts the prostate into very small/tiny pieces. These can be easily sucked out, and the obstruction in the urinary tract is removed. The results are highly promising.
Enlargement Of The Prostate
Hence it is clear that whenever the prostate becomes enlarged, it is likely to put pressure on this part of the urethra, i.e., the prostatic urethra, causing obstruction when the patient passes urine. In very early cases, there may not be any symptom or there may be negligible/minimal symptoms, since the force of the contraction of the urinary bladder may be able to overcome the small initial obstruction cause.d by the enlargement of the prostate gland.

As the obstruction increases, urine will stay in the urinary bladder for a longer period, and if obstruction is severe, urine may collect, as a result of back pressure, in the ureters, and finally in both the kidneys. One can imagine that such stagnation of urine in the whole urinary tract will cause an enormous growth of bacteria, leading to inflammation of the entire urinary tract, from the urethra to the kidneys. There will then be inflammation of the urethra (urethritis), the urinary bladder (cystitis), the kidneys (pyelonephritis) and even the prostate may be affected by the infection called prostatitis.

If early steps are not taken, kidney failure may occur as a result of the chronic infection of the kidneys, i.e. chronic pyelonephritis.

Regarding cancer of the prostate, it has already been described in the chapter on cancer. Here we are dealing with the 'benign' enlargement of the prostate, i.e. the condition is non-cancerous in nature. Such an enlargement of the prostate occurs in old people, usually after the age of 50. It has been rightly said that as the hair turn grey, there is, likewise, an enlargement of the prostate gland.

What are the early symptoms and signs of the BEP?

Since an enlarged prostate causes obstruction in the flow of urine in the urethra, the patient experiences varied difficulties while passing urine. There is a narrowing or decrease in the calibre of the urethra, and, therefore, (i) the patient does not pass urine with normal force, and the stream becomes thin, (ii) he experiences difficulty both while starting and stopping urination, (iii) he always feels that he has not passed the whole urine, (iv) urine falls in drops/trickles after he has passed urine, (v) the patient passes urine frequently, especially during the night, (vi) he takes more time in passing urine, (vii) he always feels like passing urine, and it becomes unavoidable most of the time.

The above early- symptoms and signs must be known by old people, so that they can report it to their physicians/ surgeons for early diagnosis and treatment, and save themselves from the grave complications of UTI.

As the prostate enlarges more, and the calibre of the urethra decreases further, the patient experiences more and more inconvenience while passing urine.

One factor is of great importance in such a diagnosis. If the patient is unable to pass urine completely, there is a strong possibility of 'residual urine' in the urinary bladder. This increases as the disease progresses. Residual urine is a valuable guide and indicates the severity of blockage in the urethra. The amount of residual urine is measured with the help of ultrasonography, and the line of action of the treatment is decided. Residual urine, more than 40-50 ml in the urinary bladder, is considered significant, and at this stage, treatment should not be delayed further.
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