Obesity is a wide spread dietary disorder, which has cut across all age groups. The unfortunate phenomenon being that obesity is often tagged with other health related risk factors like heart ailments, diabetes, high blood pressure amongst others. Apart from health hazards it accompanies, obesity also can make the butt of everyone’s jokes and pull down your self-confidence. If you are one of the victims of obesity, Lorcaserin which is a new generation weight loss drug can ease your worries.

This drug, Lorcaserin hydrochloride (APD356) was discovered by Arena Pharmaceuticals, Inc., a sensitive 5-HT2C serotonin receptor agonist under assessment for the supervision of obesity. 5-HT2C serotonin receptors are located in the hypothalamus, a region of the brain that controls food intake and metabolism. It was anticipated to kindle the 5-HT2C receptor and has around 100-fold selectivity in vitro for the 5-HT2C receptor relative to the 5-HT2B receptor.

Lorcaserin is a highly selective amalgam which targets a particular serotonin receptor situated in the hypothalamus, a region of the brain recognized to impact satiety and manipulate metabolic rate. It is an orally controlled drug.

In accordance to researches, Lorcaserin has long-established admirable weight loss

results, attached with outstanding tolerability and an positive impact on associated physical measures and most lipid confines among obese populace. The activation of the 5-HT2B receptor is connected with the cardiac valvulopathy administered with non-selective serotonergic agents. The strategy for appetite containment and weight control is supported by animal pharmacology and human clinical studies. In concurrence with this, Lorcaserin hydrochloride has something like 15-fold selectivity in vitro for the 5-HT2C receptor in opposition to the 5-HT2A receptor. It is believed that the 5-HT2A receptor adds up to the plausible central nervous system undesirable effects linked with non-selective serotonergic agents.

Lorcaserin hydrochloride is well tolerated drug at all doses as looked into in the trials reflecting no noticeable effects on heart valves or pulmonary artery pressures. Though some lesser Lorcaserin side effects can be enumerated as:

§Nausea

§Dizziness

§Vomiting

§Urinary tract infection

§Dry mouth

§Fatigue

§Headache

§Nasopharyngitis

The occurrence of these side effects is a consequence of bodily changes in effect to Lorcaserin medication. In case, these or any other side effects surface kindly consult your doctor for immediate medical attention. Nursing mothers, pregnant women, or women who intend to conceive should abstain from Lorcaserin medication.

It is advisable that you should consult your doctor before undertaking Lorcaserin medication to avert any medical mishap.