For more information regarding Non-Hodgkin's Lymphoma and its forms and treatments visit: www.lymphoma-net.org, stroke.www.life-threatening-diseases.com, Chinawww.4uherb.com. Mantle cell lymphoma is a fast growing tumor that spreads through the body in fact is a rare form of Non-Hodgkin lymphoma which is not very easy to diagnose. It has a very rapid evolution and reaches all the parts of the body.
That's why chemotherapy is the most indicated treatment because injected through the veins can be dispersed in the whole body. Radiation therapy has a limited indication in the treatment of Mantle Cell Lymphoma. Surgery can remove tumor from only one part of the body that's why is not recommended.
CHOP is a combination of four drugs and is administered in a single day, and repeated every 3 weeks for 6 to 8 cycles. But, there are many other combinations of chemotherapy drugs which are administered as tablets or intravenous at every few hours or days and each cycle is repeated once or more times week.
It is not an easy job to cure Mantle cell lymphoma because very often it doesn't respond to any kind of treatment and the combination of drugs have shown much toxicity and even intolerable for some patients.
Your doctor should decide whether a kind of treatment is proper or not to treat your Mantle cell lymphoma. In addition to chemotherapy, biological therapy has proven successful results in most form of lymphoma. It involves monoclonal antibodies which identify cancer cells and kills them. Rituximab has been used in most of the Non-Hodgkin lymphoma and in mantle cell lymphoma with good results and proved efficacity.
Mantle Cell Lymphoma and new medicines:
Bortezomib is a drug that has effect on proteasomes and hasten the death of the tumor cells.
Another possible treatment that has been taken into consideration is the bone marrow transplant. If a donor is found after chemotherapy, bone-marrow and stem cell transplants is a solution. But, considering the fact that usually patients with mantle cell lymphoma are old and they are not able to receive the transplants. This procedure is an alternative for some patients.
Mantle Cell Lymphoma and radiation therapy
After chemotherapy radiation to the affected area, radiation may be of a good effect, especially if the disease is in an early stage and it has not affected the whole body.
In fact, mantle cell lymphoma is not curable even if it may have a good initial response to chemotherapy, but after months or years the disease has severe manifestations. The idea of the treatment is to offer quality to life and keep that apparent health as long as possible. Because the science is revolutionary your doctor may advise you to participate in clinical trials and test new treatments.
Mantle Cell Lymphoma Treatment
A rare form of the Non-Hodgkin disease is the Mantle cell lymphoma. This disease is quite dangerous because its tumor grows very fast and ends up affecting most of the organs.
Generally, people are diagnosed with mantle cell lymphoma only when the disease has affected more organs and so, treating them is a little bit difficult because several areas of the body must be treated in the same time. The most indicated treatment in this case is chemotherapy.
Chemotherapy tries to stop cancerous cells from growing or dividing. There can be used oral drugs or drugs injected into the vein or muscle that will reach the cancer cells by entering the bloodstream, and is called systemic chemotherapy. In mantle cell lymphoma doctors use a combination of four drugs administered in a single day and then repeated every 3 weeks for 6 times.
In most of the cases, mantle cell lymphoma therapy is not useful and even if the response to the treatment seemed to be good, the disease comes back very often. In preventing this, doctors have used different drug combinations and the most successful was one treatment used in leukemia too. This treatment is unbearable for many of the patients due to its side effects, and doctors will not recommend this drug combination if they feel that the patient will not tolerate the treatment.
In most cases, after chemotherapy is done, stem cells previously taken from the patient's blood or bone marrow or from a donor will be thawed and replaced through an infusion, in order to restore the body's blood cells destroyed by the chemotherapy.
Biological therapy has proved to be useful in treating many forms of lymphoma, and it uses monoclonal antibodies. These antibodies are made from an immune system cell and are designed to seek and destroy all the substances that can help cancer cells to grow and develop. One of the monoclonal antibodies used in treating Non-Hodgkin lymphoma is Rituximab. This antibody could be used in treating mantle cell lymphoma too.
There have been developed some new drugs but they are still under tests in clinical trials. Bortezomib is one of them and using it seems to lead to the death of cancer cells.
Using radiation therapy proved to be inefficient because it did not lead to a remarkably extinction of the cancer cells and it only weakened the human organism.
Until now there is no cure for this disease and no certain effective treatment. In order to discover a useful therapy, doctors will encourage you to join a clinical trial and help them improve the medical treatment of this terrible disease.