NuvaRing birth control is a combination hormonal contraceptive. It is manufactured by Organon USA. NuvaRing is a polyethylene vinyl acetate ring around 2 inches in diameter. It is worn in the vagina for three weeks and then removed for one week. The ring contains a combination of the hormones estrogen and progestin. NuvaRing birth control slowly releases the hormones into the bloodstream. The progestin is absorbed and prevents the ovary from releasing an egg. In addition, the uterine lining becomes thinner and the cervical mucous becomes thicker. NuvaRing is considered a third-generation contraceptive.
Oral contraceptives are usually made up of a mix of synthetic female hormones. First-generation birth control pills, first introduced in the 1960's, had high levels of the hormones estrogen and the progestogens lynestrenol or norethisterone. The early contraceptive pills caused a fairly high number of blood clots resulting in blockages in the legs, heart, and brain. These blockages can then lead to heart attacks and strokes.
Second generation birth control pills were formulated to decrease the risk of blood clots. They contained lower amounts of estrogen and a different progestogen called levonorgestrel. The downside to these second generation contraceptive pills was that they caused side effects such as acne, hirsutism (increased hair growth), weight gain, and higher cholesterol levels. Second and third generation oral contraceptives differ in their progestin component.
Third generation birth control pills such as NuvaRing were developed in the 1980's to contain the progestogen hormones desogestrel or gestodene. The goal was to help reduce adverse effects such as hirsutism and acne. It is estimated that 7.5 million women filled prescriptions for third generation oral contraceptives in the United States in 2006. Studies have found that women using third-generation oral contraceptives have an increased risk of venous thromboembolism (blood clot) compared to users of second-generation contraceptives containing levonorgestrel.
Some researchers are questioning whether third-generation contraceptives such as NuvaRing are more safe and effective than second-generation contraceptives given the increased risk of blood clots. The focus has been on desogestrel, the synthetic form of the hormone progestin. Desogestrel appears to cause resistance to one of the anti-coagulant proteins (Protein C). When coagulation is inhibited it makes it easier for blood clots to form which increases the risk of venous thrombosis.
Not Using Birth Control
NuvaRing Background
NuvaRing is a form of contraceptive. It is a flexible, transparent ring that is approximately two inches in diameter that is inserted into the vagina. NuvaRing's position in the vagina is not critical for its function. NuvaRing is left in the vagina for three weeks and then removed. After one week, during which time withdrawal bleeding usually occurs, a new NuvaRing is inserted for another three-weeks.
NuvaRing is produced by Organon USA, a pharmaceutical company owned by the multi-national conglomerate Akzo Nobel. Akzo Nobel is headquartered in the Netherlands, where NuvaRing was first approved in February 2001. The drug was approved by the United States Food and Drug Administration (FDA) on October 3, 2001.
How NuvaRing Works
NuvaRing has two types of hormones ? an estrogen and a progestin. It is a third generation birth control that uses a different form of progestin than older contraceptives called desogestrel. The hormones are released into the bloodstream through the vaginal walls, which absorb the hormones and place them into the bloodstream. These hormones are designed to prevent the ovaries from producing mature eggs. Further, the lining of the uterus becomes thinner which impedes implantation of a fertilized egg.
NuvaRing Effectiveness
In three clinical trials of 13 cycles of NuvaRing use, the pregnancy rates were between one and two women out of 100. The manufacturer of NuvaRing claims it is highly effective ?when used as directed.? There are side effects, however, and some are serious.
Studies concluded as early as 1995 that the third generation contraceptives containing desogestrel had almost double the risk of venous thrombosis (blood clots) than second generation oral contraceptives. The FDA confirmed this risk in 1995 stating that ?new studies indicated that a two-fold increase in the risk of venous blood clots associated with products containing desogestrel.? There currently have been no non-industry sponsored studies comparing the benefits of third generation contraceptives such as NuvaRing to second generation ones.
NuvaRing's Side Effects
Common side effects reported by NuvaRing users are vaginal infections and irritation, vaginal secretion, headache, weight gain, and nausea. More serious side effects include a higher risk of venous thrombosis (blood clots), which could lead to a stroke or heart attack.
Studies have shown a link between desogestrel and a higher risk of blood clots and stroke. NuvaRing has been associated with blood clots including pulmonary embolism and deep vein thrombosis, as well as stroke and heart attack.
NuvaRing Lawsuits
Individuals, couples, and families are filing lawsuits on their own for serious problems caused by NuvaRing. There currently is no class action lawsuit against the manufacturer of NuvaRing for problems associated with NuvaRing's use. However, the number of these lawsuits is increasing and someday there may be a class action. If you or a loved one has suffered NuvaRing side effects including blood clots, stroke, or heart attack, you may be able to file a NuvaRing lawsuit.
Both Steve Fields & Matthew2 Peschong2 are contributors for EditorialToday. The above articles have been edited for relevancy and timeliness. All write-ups, reviews, tips and guides published by EditorialToday.com and its partners or affiliates are for informational purposes only. They should not be used for any legal or any other type of advice. We do not endorse any author, contributor, writer or article posted by our team.
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