Pramlintide is a generic name for Symlin. It is an injectable drug which can facilitate you to reduce the sugar (glucose) levels in the blood. In essence, it is a synthetic hormone similar to amylin, which is created by the pancreas to manage blood glucose level. It is primarily beneficial for treating both Type 1 and Type 2 Diabetes. It also reflects a noteworthy result to condense appetite, thus acting as a weight loss drug. It received its FDA endorsement in March, 2005 adds to its dependability.



It works by retarding the making of glucose by the liver by restraining the action of glucagon, to control the manufacture of glucose by the liver. It basically retards the pace at which food constituting glucose is absorbed from the intestine. Symlin works in three distinct ways to smooth out the post-meal max out in blood sugar. Symlin firstly, slows down the momentum at which sugar exists the stomach. Secondly, Symlin reduces the amount of sugar that penetrates into the bloodstream from the liver. Lastly, it works indirectly to lessen the magnitude of sugar that enters the bloodstream by reducing appetite so that less food and, in turn a lesser amount of sugar is consumed.

Pramlintide is habitually used in consensus with other drugs to treat both Type1 and Type 2 Diabetes. Type1 refers to diabetics who necessitate insulin to harmonize their normal insulin fabrication. Such patients should start Pramlintide medication with 15'g up to 60'g, as tolerated. Type 2 refers to diabetics whose normal production of insulin lapses. Such patients should initiate with 60'g up to 120'g as necessitated.

This medication should be presented subcutaneously in the skin prior to the major meals. Discuss with your doctor if you are engaged in drugs, which can slow down the intestine or absorption of food. Expectant women and nursing mothers should seek advice from their gynecologist prior to Pramlintide treatment.

Most common Pramlintide side effects can be enumerated as:

?Hypoglycemia

?Vomiting

?Nausea

?Fatigue

?Abdominal pain

?Headache

In case you encounter these or any other side effects consult your doctor for immediate medical assistance. Kindly consult your doctor before embarking upon Pramlintide treatment

Unopened vials of Pramlintide should be refrigerated between 2-8°C (36-46°F). Opened vials of Pramlintide should either be refrigerated or kept at a room temperature (no greater than 77°F, 25°C) and used within a span of 28 days.

Symlin therapy should only be undertaken by patients with insulin-using type 2 or type 1 diabetics who have failed to achieve adequate glycemic control despite individualized insulin management and are receiving ongoing care under the guidance of a healthcare professional skilled in the use of insulin and supported by the services of diabetes educationalist.