Rheumatoid arthritis is the commonest inflammatory arthritis with an incidence of about one percent in the population. A chronic disease which affects the whole body, it presents with a symmetrical arthritis of many joints and involvement of other tissues such as the lungs, heart, eyes and skin. Prominent morning stiffness, tiredness and malaise are common due to the systemic nature of the disease and as it destroys joint structure it can be accompanied by a high level of disability. Recent advances in scientific understanding of arthritis and newly developed drug therapies have improved the outlook for sufferers. The cause is unknown but infection is often suggested.
As rheumatoid arthritis is responsible for high levels of disability, disease complications and increased mortality, it is not a benign process. As activities of daily living (ADL) can be badly affected about a third of patients are unable to work after 5 years since their diagnosis and after ten years 50% typically have an important loss of ability to function. The rheumatoid complications and therapy side effects may result in a shorter life span by five to ten years, RA occurs across ethnic groups and is more common in women in a ratio of three to one. The peak time for diagnosis is between thirty-five and fifty years but RA can be diagnosed in children and in elderly persons.
Rheumatoid arthritis diagnosis is made by the doctors clinical examination and by the self report of the patient rather than laboratory tests. A typical complaint is severe stiffness in the morning, remaining for an hour or longer until it improves as much as it is going to. Three joint areas must be affected by the swelling and pain of arthritis, with a symmetrical joint presentation and involvement of the hand small joints. Usually the disease comes on slowly but sometimes there is an acute, sudden onset of severe joint swelling and pain. Typical symptoms also include losing weight, feeling below par, a fever and muscle pain.
Treatment of rheumatoid arthritis is complex and involves a multi-disciplinary team approach. Patient education is vital so they can understand a complex disease with many and severe consequences which can affect functional abilities profoundly. Physiotherapists work to reduce inflammation and pain, maintain joint ranges of motion and maintain and increase muscle strength. Occupational therapists may teach patients the principles of joint protection in functional activities, suggest aids to daily living, make resting splints for inflamed joints and advise on adaptations to a patients home. Many patients come to joint replacement as the disease process is very destructive.
Initial treatment is often with anti-inflammatory and painkilling medication until DMARDS (disease modifying anti rheumatoid drugs) take effect. These drugs can hold back or prevent progression of the disease, reducing the likelihood of joint destruction with accompanying loss of functional ability. DMARDS have developed over the last few years into the biological agents based for the first time on a scientific understanding of the underlying pathological process. This has raised the hope that the disease process can be stopped, preventing many of the disabling consequences of RA quite apart from the pain. These drugs are having dramatic effects on the lives of people with rheumatoid arthritis.
Rheumatological assessment by a physio begins with observation of the ability to walk as they attend the appointment and the noting of deformities of the joints. The hands, knees and wrists commonly suffer deformities, particularly bad at the knuckle joints, which interfere badly with hand function and the ability to exert force in grip and manipulating objects. RA can severely impair walking ability due to pain and postural abnormalities of the feet, knees and hips and walking aids are often necessary, although shoulder, elbow and hand problems interfere with the ability to use crutches or a frame.
Initially, as the joints are inflamed and painful, physio treatment aims to rest the joints, reduce inflammation and pain, protect the joints with splints and to maintain function by gently joint exercise. When the condition becomes sub-acute the physiotherapist will include range of motion exercises and strengthening along with functional work. Successful management of RA requires a cross-disciplinary co-operation due to its complex nature.
Treatment Of Rheumatoid Arthritis
Unlike osteoarthritis, rheumatoid arthritis is an inflammatory, not degenerative, disease. It first appears as an inflammation in a joint's synovium, the membrane that lines and lubricates the joint. Once inflamed, the membrane thickens and become sore and swollen-which in turn may limit the affected joint's movement. In time, this inflammation spreads to other parts of the affected joint, causing even more stiffness and pain. Eventually, the inflammation can spread to organs, such as the heart, lungs, and eyes. Its ability to spread throughout the body makes rheumatoid arthritis a systemic disease-a disease that affects the entire body.
Inflammation is not a harmful state, per se. It's actually your body's normal response to infections and injuries, caused when your white cells battle an invading organism. Typically, the inflammation subsides after the infection is wiped out. However, with rheumatoid arthritis, the autoimmune system seems to fight the body instead of protecting it.
While the disease can strike at any time, it usually occurs between the ages 20 and 50. It affects approximately three times as many women as men.
Unlike illnesses that have a set progression of symptoms, rheumatoid arthritis is unpredictable. What symptoms appear, how often they appear, and what joints and organs are affected vary widely, depending on the individual. In some sufferers, rheumatoid arthritis will flare up occasionally, only to be followed by periods of normal health. Others experience recurring attacks without returning to a state of full wellness in between. Many experience a slow and steady increase in the severity of their symptoms over time.
Some people with rheumatoid arthritis develop small lumps under the skin near the elbow, ears, or nose, or on the back of the scalp, over the knee, or under the toes. Called rheumatoid nodules, these painless and non-problematic bumps range from the size of a pea to the size of a Ping-Pong ball.
While medical experts have not identified a single cause for rheumatoid arthritis, possibilities include heredity, viral or bacterial infection, and emotional stress.
Signs and Symptoms
Pain, swelling, redness, and warmth in the affected joint-most commonly affects the smaller joints of your hands and feet, but elbows, knees, and ankles can be affected
Usually affects joints symmetrically (both hands, for example)
Overall stiffness and achiness, especially after periods of stillness, such as sleeping or long plane rides
Symptoms are worse in the early morning and lessen as the day progresses. General malaise/weakness
Anemia
Pain usually occurs during rest and movement
Conventional Medical Treatment
A series of blood tests, along with a thorough physical exam and medical history, can confirm whether you have rheumatoid arthritis. X-rays may also be helpful. Strategies for treating rheumatoid arthritis differ, depending on whether it is active or in remission. During a flare-up, a combination of rest, heat, and medication is prescribed. Anti-inflammatory drugsaspirin, in particular are the first line of treatment and may ease symptoms. There are several other medications used to treat rheumatoid arthritis. Your doctor may prescribe gold salts, penicellamine, methotrexate, azathioprine, or anti-malarials, depending on how your symptoms progress. Corticosteroids can temporarily relieve pain and inflammation, but they are usually reserved for those with more serious disease.
Physical therapy plays a major role in the treatment of rheumatoid arthritis. It is most effective when swelling and inflammation of the joint are suppressed with medications. Physical therapy can reduce deformity and restore function.
In severe cases, surgical removal of affected joint lining can prevent damage to other joint structures and cartilage. Another surgical procedure fuses the painful, uncushioned bones together but is only performed on the wrist, feet, ankles, and thumbs because it restricts motion. Tendon transfer is another surgical option for repairing damaged tendons and ligaments it is performed most frequently on the hands. Another option is arthroplasty, or joint replacement, which is usually performed on knees, hips, and shoulders.
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