Cord blood, also known as placental blood, is the blood that remains in umbilical cord and placenta following a live birth. There are 3 sources of stem cells: umbilical cord blood, embryonic cells and bone marrow. Adult stem cells from bone marrow have limited uses while embryonic stem cell research is a major area of controversy. Umbilical cord blood stem cells are more proliferate and can be successfully substituted for embryonic stem cells in research and treatment.
There are advantages to using cord blood stem cells:
- It is easy to collect cord blood without posing any risk to the newborn or mother. Cord blood banking allows stem cells to be frozen and stored for immediate use in the future. This is not possible with bone marrow donation since it takes time to find a matching and willing donor.
- As cord blood stem cells are young and less mature, they can be transplanted even when there is a half match. Bone marrow transplant requires perfect match between donor and recipient.
- Cord blood stem cells are less likely to attack the patient's own tissues than bone marrow stem cells. There is also a reduced likelihood of transmitting certain viruses when cord blood is used.
Umbilical cord blood stem cells have the potential to develop into many types of cells such as muscle, nerve or blood cells. Cord blood stem cells are able to regenerate immune system and replace damaged or diseased cells. Currently, cord blood is being used to treat blood disorders, certain cancer and auto-immune diseases.
While much research still needs to be done, there have already been some significant advances in stem cell therapies. Researchers are looking into the ability of cord blood stem cells to replace or repair damaged tissues and organs. Since these cells can repair damaged tissues, they could be used to treat Parkinson, heart disease, stroke, spinal cord injury, multiple sclerosis and diabetes.
In recent breakthroughs of stem cell research, scientists have been able to differentiate cord blood stem cells into a type of lung cell, grow mini liver and develop bone and cartilage. These preliminary findings show that cord blood stem cells offer great potential in the treatment of lung and liver diseases, and acute kidney failure. Cord blood cells can potentially repair organs damaged by illness or disease. Due to the severe shortage of organ donors, these cells could be transplanted into the body in much the same way organ transplants are done today. Scientists are hopeful that these cells will regenerate into organs in the human body.
Umbilical cord blood is still in the early stages of use in scientific and medical research. Studying these cells will help researchers understand how they are able to transform into a wide array of more specialized cells that make up the human body. Some of the most serious medical conditions such as cancer and birth defects are caused by problems that occur somewhere in the cell process. A better understanding of how normal development occurs and disease processes can enable researchers to develop new and improved approaches to treating diseases and injuries.
Umbilical Cord Blood And
Cord blood banking generated debates about the implications of donating against private storage of umbilical blood. Umbilical cord blood, a "miracle" in medical and scientific research, is found to contain stem cells which are highly valuable in treating blood-related diseases. Its "primitiveness" can regenerate whole immune systems necessary for curing chronic diseases like leukemia, anemia, and immune system disorders. Despite its many uses, there are limited donations made in public banks because of several reasons. Lack of equipment, incompetent information dissemination, and financial problems are common reasons. But other than these, the desire of parents to save their children's blood for familial use is a stronger reason. Most families are opting to keep stem cells as "medical insurance" in case one of them gets sick with a blood disease. If you are thinking about your options, recent studies prove that public storage is more beneficial to the donating family and others.
First, there is little chance that immediate members of the donating family can use the donated stem cells. Umbilical cord blood from the sick child himself is unsuitable for his use. The genetic materials that made the disease possible is also encoded in the blood cells. The parents also contain strains of these genetic materials which make them unsuitable candidates for the blood's use. Besides, stem cells harvested from umbilical blood are usually not enough to cure adults or persons weighing over a hundred pounds.
Second, if you do need umbilical blood, chances are higher that your match is in public stores rather than private storage. National Marrow Donor Program's Dennis Confer affirms that an exact match between a donor's umbilical blood and his sibling is pegged at only 25%, while exact matches from public stores is at 75%. He claims that the latter is higher if internationally-based cord blood banking systems are included.
Third, doctors often prefer umbilical blood procured through public banking systems. Unlike private storage, public banks have regulated and rigorous standards for umbilical cord blood preservation. They have standards on amount, sanitation, and trained, qualified staff. Private storage are just ordinary businesses - they aim for profit. They may limit the amount of harvested samples to make room for more, or hire less than qualified staff to lower manpower costs. By keeping umbilical blood in private stores, its quality is highly at risk.
Fourth, donating umbilical blood in public banks does not limit your access to it unless it was used. Public and government-regulated cord blood banking institutions give priority to donors if they need their donated blood. Also, there are very slim chances that your donated umbilical blood is used. Lawrence Petz from StemCyte - a top public/private umbilical blood bank - estimates that only 5% of banked donations are used.
Lastly, donating umbilical cord blood is more economical because it's free. Private banks charge as much as $2,000 for collection and registration, and another $100 yearly for storage. That's a lot of money for something you might not even use. But by donating umbilical blood to cord blood banking institutions, you are giving a chance at life to other people without expense on your part. You never know but the life your donated umbilical blood saves might be the your savior in the unforeseen future.
Both Alvin Toh & William Teleo are contributors for EditorialToday. The above articles have been edited for relevancy and timeliness. All write-ups, reviews, tips and guides published by EditorialToday.com and its partners or affiliates are for informational purposes only. They should not be used for any legal or any other type of advice. We do not endorse any author, contributor, writer or article posted by our team.
Alvin Toh has sinced written about articles on various topics from Bull Terrier Dogs, Fitness and ADHD. Cord blood stem cell transplant is becoming increasingly important for treatment of life-threatening diseases and debilitating conditions.
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