The definition of a "clicker" is simply a person who chooses to bind little to no key bindings. Some might argue they don't need bindings for an MMORPG, as are slow paced at times. This is just plain stupid.
Clicking all your abilities would be like trying to type an email with a single finger. Memorizing a solid set of key bindings is going to be extremely important and is a key factor in determining your final level of success.
The fewer abilities you have to click the better, binding all your abilities to hotkeys is crucial. For most of us, your left hand rests on the keyboard, positioned on home row. This should be your starting base for all your key bindings. Q, W, E, A, S, D by default are all your movement keys, even though you'll primarily be using the mouse to move and change camera angles, having these keys bound to their original functions is important so you can continue moving while switching targets (since Tab target is hopelessly broken). As your mouse will be your primary camera angle adjuster you may choose to move your strafe keys from Q and E to A and D, thus opening up additional easy binds.
Depending on the length of your hand you'll have to decide what will be the farthest reach for you, it will likely be 5, 6, or 7. Now draw an imaginary line down from that key and this is what will be, for lack of a better word, your WoW home row. The biggest thing to remember when your binding keys is that they need to be easy for you to hit, you don't want to have to think about them or strain at all in clicking them. They all will have to be second nature to you, so it's no longer a matter of adding a second variable of hand eye coordination into the choosing of a spell or ability.
My Key Bindings: 1-6 Shift + 1-6 F Shift + E, R, T, G, Y, F, V F1-F4 Mouse Button 4, Mouse Button 5, Scroll Mouse Button Shift + Mouse Button 4, Shift + Mouse Button 5, Shift + Scroll Mouse button
There was a time when I was more or less a "clicker", terrible I know, I had a few skills bound; sinister strike, eviscerate, kick, stuff like that, but I lacked many key abilities I needed to make myself a better player. I finally buckled down and bound everything, it took me probably two weeks to get really comfortable with everything I had bound, but in the long run it was a great decision.
I was insanely faster in Arena, a more efficient raider, and brought my game to a higher level. My bindings and techniques for learning worked perfect for me, though they might not be right for you. Try some different setups, but take the time to really learn a your keys. Trust me, learning a solid set of keys will really help you out in the long run and will make you a better player in all sects of this game.