Idebenone is one of the most potent of the six leading antioxidants, although such sources as green tea extracts that contain catechin polyphenols and a form of fat-soluble Vitamin C called Ascorbyl Palmitate are used often when manufacturing the very best anti-aging serums and creams.

Idebenone received the highest score among the six leading antioxidants, of 95 out of a 100, in a research study from the Journal of Cosmetic Dermatology. They developed the very first set of procedures while comparing the effects and efficiency of antioxidants, to determine the prevention of free-radical skin-damage.

Idebenone is a synthetic analogue of a naturally-occurring enzyme called Coenzyme Q10 (Co Q10). Co Q10 is an important antioxidant component of the lipid (fatty) membranes that surround all cells, as well as the lipid membranes surrounding the various organelles ("little organs"), such as mitochondria and microsomes, inside cells. It is cell energizer, which means it produces the required energy for cell reproduction.

However, Idebenone is different from Coenzyme Q10 in one very important way. During a hypoxic (low oxygen) condition, CoQ10 can switch function from an anti-oxidizing to an auto-oxidizing process. This auto-oxidation rapidly produces free radicals which damage the tissues of the body. Studies have shown that in such circumstances Idebenone prevents the free radical damage and maintains relatively normal cell ATP levels.

To understand the anti-aging benefits of Idebenone we must first understand the mitochondrial processes in cells. Mitochondrial cells, which contain the richest sites of Co Q10 or Idebenone, create as much as 90% of all ATP bioenergy. Mitochondria is produced from Mitochondrial DNA or mtDNA.

As we age, our levels of mtDNA endure more damage, while the production of mitochondria becomes increasingly more unproductive in their means of generating energy. The heart muscle, brain cells and skeletal muscle are the most susceptible to the depletion of mitochondrial energy as we age and the regeneration of cells begin. Consequently, the cells die and a variety of developing diseases occur as the years advance upon us.

Therefore the benefits of Idebenone, offers the result of anti-aging in several different ways. Idebenone serves as influential in reducing the free radicals of mitochondrial, while curbing the damage that occurs with aging and the increasing of mtDNA, dissimilar to Co Q10, while under conditions of low oxygen that can possibly occur throughout a lifetime. What this means is, Idebenone works much better than Co Q10, under hypoxic conditions within the chain of electron transport in keeping up the production of high energy.