There are a wide variety of lines, openers, tips, and pick up philosophies when it comes to talking with women, so here's a real-world technique that works really well. I've been using this for well over a decade, so I know this works well. It's simple, but it's not a magic bullet. You've got to apply it and practice it just like any other learned skill. Ready?
All you need is a pen, a small note pad or steno pad, and the ability to get yourself to a book store, super market, or any place that has a newstand full of magazines. Go the area where they house the magazines and start going through the ones that women usually read. Take your steno pad or note paper and write down topics that might be interesting to women. For example, "7 ways to make him love you" or "10 sure-fire signs that he is cheating on you" or "what men really think".
When I use this technique I write down a bunch of different topics. I then read the article and take notes on what I just read. When I arrive back at my house I begin working on creating openers. An opener is simply the first thing you're going to say to a woman, so even "hi" is an opener. Asking a woman her opinion about something is also an opener. While you can do this exercise on the internet, I prefer that you go out in public and do this. Why? Because this gets you out into the public! You've got to start getting used to interacting with strangers, even if simply to look at a magazine a woman is reading and then reading one of the headlines on the cover and simply asking her "can you believe there are 357 fashion tips in that magazine? I can not imagine who comes up with all those ideas, do you?"
After you've written down a few topics (the more the better, though if you are new at this keep it at around 4 to 6 topics for starters) go home and begin rehearsing your openers. For example, if you wrote down an idea for an opener based on the article "what men really think" you might start off a conversation like this:
You might start off with, "I read an article recently that talked about what men really think and I was talking about it with a friend of mine."
She replies with, "Okay."
You continue with, "Part of the article said that most men are looking for a woman that resembles their mother. They even cited a couple studies to back it up. What's your take on it?"
I've started conversations by simply saying "hi" and then following it up with something else to say. Most women know that as soon as you approach them that you are interested in them. So a great way to approach them is by asking them an opinion about something.
By making a habit of going through different kinds of magazines that women read, you will eventually have so many topics to talk about that you'll never run out of things to say. So get out there and start practicing.