IGF-1 belongs to the peptide family which has a same structure and size as insulin. It is a highly anabolic hormone that is released in the liver as well as in the peripheral tissues in response to the GH so that a new muscle could be built. The main work of IGF-1 is to build new muscle tissues by promoting nitrogen retention and protein synthesis. IGF-1 not only makes muscle fibers bigger, but also makes more of them. IGF-1 has potent effect on fat metabolism and helps the body to burn fat rapidly. It also improves mental functions such as reflexes and learning ability.

IGF-1 has a very sensitive and unstable property that's why it is used rarely because it has a very short term life of only 10 minutes. That's why a substitute of IGF-1 referred to as Long R3IGF-1 or IGF-1 LR3 is used. IGF-1 LR3 has longer life. IGF-1 life time is increased from 10 minutes to hours in IGF-1 LR3, so that the users can get away using a smaller amount of IGF-1 LR3 and does not have to use it as frequent. Long R3IGF-1 is in the form of lyophilized powder form or already reconstituted form.

IGF-1 LR3 is widely used by bodybuilders, but it not recommended for inexperienced bodybuilders. It is recommended that you should first take anabolic steroid for a long period of time before practicing IGF-1 LR3, and you should be aware the hypoglycaemic affects that it produces.

If you are using IGF-1 LR3 without any prescription or without any pre use of anabolic steroids then, be prepared to face the consequences because if you use it like that, it is going to cause several side effects, such as - cancer, accelerated growth of tumors and enlargement of intestinal organs.

IGF-1 LR3 doses range from 20mcg up to 120mcg. The initial starting dosage is 20-40 mcg. According to the reports of users, the results of Long R3IGF-1 are seen in a shorter span of time. The course length is usually 4 weeks but you can go up to 50 days off. Ideally it should be injected post workout. Injecting the drug intramuscularly is the best option i.e. injecting 20mcg into one bicep and 20mcg into the other. IGF-1 LR3 however has some adverse side effects, which include severe headache, nausea, and possible hypoglycaemia. The drug is not prescribed for persons with a history of cancer.