Hoodia gordonii looks like a cactus, but it's actually a succulent from the Kalahari Desert in southern Africa. Bushmen from the area have been using hoodia for centuries to help ward off hunger during long trips in the desert.

Hoodia gordonii is entirely natural -- it is not a drug. Pharmaceutical companies find it so promising, however, that they are trying to isolate the appetite-suppressing molecule, P57, to create a patented diet drug in the future. Only the gordonii variation of hoodia has appetite suppressant abilities. Hoodia tricks the brain into thinking you've eaten, and makes you feel full.

Hoodia may work right away, or may take several weeks.

Key results of hoodia reported include a reduced interest in food, delay in the time after eating before hunger sets in again, feeling full more quickly, and a general feeling of well-being

Hoodia gordonii is not a stimulant, and has no known side effects. Hoodia appears to be safe for most people.

There are various species of hoodia, but the Gordonii variation is the only one that contains the all-natural appetite suppressant. Tbis type of hoodia contains a molecule that has similar effects on nerve cells as glucose, and tricks the brain into the sensation of fullness. Results of human clinical trials in Britain suggest that hoodia may reduce the appetite by hundreds of calories a day or more.

In a BBC interview, Phytopharm's Dr. Richard Dixey explained how P57 works:

There is a part of your brain, the hypothalamus. Within that mid-brain there are nerve cells that sense glucose sugar. When you eat, blood sugar goes up because of the food, these cells start firing and now you are full. What the Hoodia seems to contain is a molecule that is about 10,000 times as active as glucose. It goes to the mid-brain and actually makes those nerve cells fire as if you were full. But you have not eaten. Nor do you want to.

One of the first studies of Hoodia Gordonii was done in the UK on obese patients. Half of the volunteers were given Hoodia Gordonii, the other half were given a placebo. The subjects were allowed to read, watch television and eat. After 15 days it was found that those taking Hoodia had reduced their calorie intake by 1000 calories a day. Despite having unlimited access to food, the Hoodia subjects lost weight.

Is Hoodia Safe?

Since Hoodia is a plant (versus a man-made chemical), it is completely natural and experts say it is safe to eat. Scientists have been studying Hoodia for almost 10 years and have not found any side effects. (Not to mention the San Tribesman who have been eating Hoodia for years with seemingly no ill effects).

What Can You Do?

One way to tell if a Hoodia pill is real is to look for a document called the C.I.T.E.S. Certificate (The Convention on International Trade in Endangered Species of Wild Fauna and Flora). Since the Hoodia plant is a protected plant species it can only be sold to an exporter who has this certificate.