Popular belief tells us that cholesterol is dietary in origin, however the truth is actually that it is synthesized internally. Cholesterol is generally present in higher concentrations in tissues which have more densely-packed membranes. Examples of tissue that have densely-packed membranes are: the liver, the spinal cord and the brain. Playing a central role in the biochemical process, cholesterol, is best known for the association of cardiovascular disease with various lipoprotein cholesterol transport patterns and high levels of cholesterol in the blood.