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The Biology of Hair Loss

The average human scalp is covered by 100,000 hair follicles. If you've got all your hair, that may seem like a big number but when you start to lose it, the fate of each follicle becomes more important. What makes hair fall out?

Sprouting New Locks

Today, many men turn to hair implants to cover their bald spots. And implants can look like the real thing. But as doctors remove hair follicles from where the hair is growing and implant them in spots where the hair is bare, implants in a too large bald spot make the whole head of hair look strangely sparse. That, and the length of the procedure?spanning about 16 hours in two sessions'is the reason that only two percent of men with male pattern baldness are estimated to seek out the surgery.

In the case of hereditary hair loss, as a man ages, some of his hair follicles become sensitive to the hormone dihydrotesterone (DHT), a chemical that is also partially responsible for the formation of male characteristics.

These hair follicles shrivel up and stop growing new hair. But what's not yet understood by scientists is why follicles in the back of the head never become sensitive to DHT, as hair continues growing there throughout a man's life.

To take advantage of the faithful follicles, a hair loss surgeon trained in hair cloning would remove a few hairs from the back of the head. But instead of inserting these hairs back into the top of the scalp, as in the case of transplantation, he would take them to a lab where the hairs can be broken down into individual cells and reproduced an almost infinite number of times. Those new hair cells can then be sent back to the doctor a few weeks later, where they are reinserted into the patient's scalp. In theory, the new follicles would begin to grow hair within three months. (see Hair Loss Fact)

Female Baldness

A drug used to treat male baldness could also help women with thinning hair, an Italian study suggests. Up to half of women experience some hair thinning during their lifetime.

The hair loss researchers said the Archives of Dermatology findings showed finasteride could be used for those who could not use the standard lotion treatment.