The following paragraph lists some of the most common symptoms.

Typical in-flight symptoms you may experience are ear-popping, nasal congestion, dehydration, headache, diarrhea or constipation, loss of appetite (may be caused by the in-flight food), light-headedness, problems with coordination, inability to concentrate, irritability, confusion, anxiety, fatigue, sweating, swollen lower legs and feet, and motion sickness. Some of the above symptoms can also be associated with jet lag. In addition, jet lag can also affect your sense of orientation in terms of time and place, as well as disrupt your sense of well-being.

Most medical symptoms can be easily reduced or eliminated by doing a few simple things.

If you drink plenty of water, juice, or soda, every half hour or so, it can help prevent dehydration and dryness in the throat, nose and eyes. Alcohol, as well caffeine should be avoided or consumed in moderation as they can cause dehydration and disrupt sleep patterns.

Most people's bodies tend to swell when they fly. Wearing loose clothing helps to relieve this swelling. It will also add to your in flight comfort.

Try and sit in an aisle seat so you can get up and walk around a bit. This will help the circulation in your legs and reduce the chance that you will develop a serious medical condition called deep-vein thrombosis.

If you experience jet lag when you fly, you may want to consider taking a melatonin tablet or capsule in the early evening (your time) to help you adjust to the time zone at your destination. You may still have to take a dose of melatonin for the next three or four evenings in a row before you go to bed in this new location to help you readjust your biological clock. If you have never taken melatonin before, you should ask your doctor or local pharmacist for more information in regards to the suggested dosage.