Save Money With Your Book Design & Layout Most people don't think of the layout design of their book as an area that can impact the printing cost, but it can have an effect.Printers print pages in blocks, called signatures. A 32-page signature is most common, so if your page count is divisible by 32, that's the most economical option possible. However, the general rule of thumb is to try to not print less than a quarter signature of 8...... Similar Editorial : by Angela Donelle Underwood. | Source : Online Periodicals