The articulations represent the connection of at least two bones. The heads of these bones are covered in a durable, elastic substance- the cartilage, which minimizes their friction and absorbs forces. The articulation is protected by the joint capsule that also has the role to stabilize it. Within these devices, there is a synovial membrane, containing the synovial fluid that nourishes and lubricates the cartilage, to ensure a proper function.
Rheumatoid arthritis represents the chronic inflammation of the articulations, caused by the attack of the organism's own immune system on the articulations, a partly similar reaction to an allergy. The result is permanent, progressive and painful.
Synovium is one of the healthy components attacked by the released enzymes. It inflames and generates pain.
Symptoms
Women are three times more at risk than men. The first to be affected are the small articulations of the hands and feet; usually more articulations are attacked at the time. The symptoms worsen in the morning. 25% of the cases of rheumatoid arthritis develop subcutaneous pea-sized nodules. They are made of scar tissues and other products additional to inflammation. They don't hurt but they may appear in the ankles, the back of the skull, the back of forearms or in the elbows.
The systemic character of this disorder also generates. Additional symptoms, besides pain and rigidity: fever, anemia or muscle aches. These symptoms should not be neglected, as general as they may seem.
How is it diagnosed?
Although the X - rays are unable to diagnose RA, their purpose is to eliminate the possibility of other disorders.
The Latex test is the most common procedure at this respect. It identifies the blood anti bodies called rheumatoid factor present in blood only in case of synovial inflammation. Even if it may not show from the very beginning, the test is positive for the majority of the people affected by RA. It can also indicate other diseases but the cases are very rare.
The second step that follows the diagnosis is to determine the conditions activity by means of a sedimentation rate test which implies the drainage of the blood, to allow it to settle for a blood. Inflammation is indicated by a high rate of sedimentation. A follow-up test is necessary to indicate whether the inflammation increases or decreases. The results determine the necessary treatment.
The treatment of the rheumatoid arthritis
The treatment uses, in the beginning, non - steroidal anti inflammatory drugs like Advil or Aleve to determine the inflammation and the pain to retreat. Because of their side effects, involving gastrointestinal and cardiovascular problems, the doses must be very carefully measured. To prevent the disorder from progressing, methotrexate is often used.
Besides injectable corticosteroids, stretching exercises are also necessary. No more than 3 corticosteroid injections are recommended because they don't have effect any longer or may even increase the damage.
Because rheumatoid arthritis is a very complicated disease, the patient, his or her podiatrist, the general physician and the rheumatologist must work together in order to determine the most appropriate treatment.
Management Of Rheumatoid Arthritis
Not affecting the tissues around the joints, but the lymphatic tissues, lymphoma is a type of cancer that leads to weak immunity for the human body and affects the lymph nodes. The white cells, especially the plasma ones can't end their mission of locating and destroying antigens or foreign materials because of the malignant or lymphoma lymphocytes that divide and enlarge the lymph nodes or other organs like stomach or intestines.
Is being well known that lymphoma makes more victims around men who past the age of 60, while rheumatoid arthritis chooses women. Trying to determine a connection between these two diseases we can easily figure out that the risks for a person to have both these diseases are low.
After further research scientists obtained a conclusion quite different from what we had imagined earlier. Patients with rheumatoid arthritis have chances to develop lymphoma. Their chances grow with their stage of disease. For a low degree rheumatoid arthritis patients the risk of developing lymphoma is not so high, but for those with a moderate or high level of rheumatoid arthritis the chances to develop this type of cancer are real high.
Archive notes tell us that in the last 30 years a insignificant percentage of rheumatoid arthritis patients suffered from lymphoma, being counted a number of less than 400 patients.
Patients with a very severe form of rheumatoid arthritis risk to develop lymphoma more than the other cases.
Most of all, the later studies show us that the treatment for rheumatoid arthritis has no connection with the development of lymphoma. The study was made over a rheumatoid arthritis specific treatment including methotrexate, oral steroids, anti-inflammatory drugs and aspirin.
Despite this study we can still hear opinions about the connections between rheumatoid arthritis treatment and the development of lymphoma, as a consequence.
Perhaps we have to take these opinions seriously, even though the two diseases rheumatoid arthritis and lymphoma refer to different types of patients, because both of them affect tissues and stop the white cells to take care of the immune system. That's why patients with moderate or severe rheumatoid arthritis should talk to a specialist that could help them reduce the risks of lymphoma.
Both Ethan Armitage & Groshan Fabiola are contributors for EditorialToday. The above articles have been edited for relevancy and timeliness. All write-ups, reviews, tips and guides published by EditorialToday.com and its partners or affiliates are for informational purposes only. They should not be used for any legal or any other type of advice. We do not endorse any author, contributor, writer or article posted by our team.
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