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Need To Know Addon

    View: 
What is Tuberculois (TB)?



Tuberculosis (abbreviated as TB for tubercle bacillus or Tuberculosis) is a common and deadly bacterial infection caused by mycobacteria, mainly Mycobacterium tuberculosis. Tuberculosis most commonly attacks the lungs as pulmonary TB but it can also affect the central nervous system (brain), the lymphatic system (lymph nodes), the circulatory system (heart), the genitourinary system (kidneys), bones, joints and even the skin. Other mycobacteria such as Mycobacterium bovis, Mycobacterium africanum, Mycobacterium canetti, and Mycobacterium microti can also cause tuberculosis, but these species do not usually infect healthy adults.

TB has been a serious public health concern for a long time now. Back in the 1800s, this disease was responsible for over 30% of all deaths in Europe. With the advent of anti-tuberculosis medications in the 1940s, the fight to eradicate tuberculosis seemed to have been won. Unfortunately, due to other contributing factors such as a shortage of public health resources, reduced immune response due to Acquired Immunodeficiency Syndrome or AIDS, drug resistance development, and extreme poverty in different parts of the world, tuberculosis continues to be a deadly disease. Around the world, there are 8 million new cases of symptomatic tuberculosis and 3 million deaths from this disease every year. It is believed that a third of all the world's population have a dormant (latent) tuberculosis infection, although only about five to ten percent of that statistic progress to active tuberculosis disease. The World Health Organization predicts that if left unchecked, TB will kill 35 million people in the world over the next 20 years.

How is this disease passed on?

TB is transmitted from person to person, usually by inhaling bacteria carried along in air droplets. When a person with TB coughs, sneezes, or speaks, small particles that carry two to three moisture-coated bacteria are released in the air. When another person inhales these particles, the bacteria may lodge in that person's lungs and multiply. Persons with long-term, constant, or intense contact to people with tuberculosis are at highest risk of becoming infected with an estimated 22 percent infection rate.

A less common means of bacteria transmission is through the skin. Doctors and laboratory technicians who deal with TB specimens may contract the disease through accidental pricking of infected needles or direct specimen contact on skin wounds. TB has also been reported in people who have received tattoos and people who have been circumcised with unsterilized instruments.

It usually passes from person to person through watery airborne droplets of coughs, and in the mucus that infected persons cough up from their throats. About one third of the world's people (including 10 to 20 million in the US) have been infected with TB. The incidence of childhood TB increased by 40% in a 6 year period (1987 to 1993) in the US as a result of poverty, immigration and HIV infection.

What symptoms should I watch out for?

The initial onset of tuberculosis may be symptom-free, or the individual may just experience flu-like symptoms. In the secondary stage, also called the active disease, sufferers might manifest a slight fever, night sweating, weight loss, fatigue and various other symptoms, depending on the body part affected. Pulmonary tuberculosis is usually associated with having a dry cough that eventually leads to a productive cough with bloodstained sputum. There might also be chronic pain in the chest and shortness of breath. This secondary stage, if affecting the lungs, is the contagious stage. This is when the bacteria can be spread to others.

Is there a cure for tuberculosis?

Doctors will need to gather a thorough medical background and perform multiple tests in order to detect if you are indeed infected with the virus. Medications may be prescribed depending on the type of tuberculosis you have. However, for severe cases of infection, surgery might be required to either introduce air into the chest to collapse the lung, or removal of a part of or the entire affected lung.

Don't take your body for granted. After all, we only have one body to use for what little time we have to live. Considering that the environment we live in isn't as clean as it used to be, and that more and more diseases are getting discovered every day, it ought to be up to us to take care of our own health.
Need To Know Addon

What is a tubal pregnancy?
An ectopic pregnancy, commonly known as a tubal pregnancy, is a pregnancy in which the fertilized egg implants itself somewhere other than the uterus. It is referred to as a tubal pregnancy because 95% of ectopic pregnancies occur when the fertilized egg is unable to travel all the way through the fallopian tube to the uterus, and therefore implants itself in the tube.

Of all ectopic pregnancies, 1.5% are abdominal, 0.5% are ovarian, and 0.03% are cervical. None of these places are suited for a growing baby. As the fetus grows, it can eventually burst the organ that contains it, causing severe internal bleeding, and endangering the mother's life. Unfortunately, a tubal pregnancy will never develop into a live birth.

Although there have been advances in surgical technology that have caused the death rate due to tubal pregnancy to drop since 1970, there is still a death rate of about 1 out of 2000, with about 40-50 women dying each year in the U.S.

What causes tubal pregnancy?
There are many reasons why an egg may become lodged in the fallopian tube. It is most often caused by an infection or inflammation of the tube that partially or entirely blocks the passage. Pelvic inflammatory disease (PID) is the most common of these infections.

Endometriosis, when cells from the lining of the uterus detach and grow elsewhere in the body, can cause blockages. Scar tissue from previous pelvic or fallopian surgery can also lead to tubal pregnancy. Less frequently, abnormal growths or birth defects can alter the shape of the tube and obstruct the egg's progress.

How will I know if I am having a tubal pregnancy?
It can be difficult to recognize symptoms of tubal pregnancy since many of the early signs mirror those of a normal pregnancy, such as missed periods, breast tenderness, nausea, vomiting, or frequent urination.

Some of the symptoms more specific to tubal pregnancy are:

  • Pain in your lower belly
  • Slight bleeding from vagina
  • One-sided pain in your stomach
  • Shoulder pain (which may be caused by internal bleeding irritating your diaphragm when you breathe)
  • Bladder or bowel problems
  • Feeling light-headed or faint, sometimes accompanied by paleness, increased pulse, diarrhea, and falling blood pressure (caused by blood loss)
  • Abnormal bleeding (heavier or lighter than usual and prolonged, or dark and watery, almost like prune juice)
  • Lower back pain

If you experience any of these symptoms you should go directly to the emergency room. If you arrive at the hospital complaining about abdominal pains, you will most likely be given a pregnancy test. Urine pregnancy tests are not necessarily the best pregnancy tests, but they are fast. Speed can be crucial in dealing with a tubal pregnancy.

If the pregnancy test comes back positive then your doctor will probably perform a quantitative hCG test to measure the amount of human chorionic gonadotropin in your body. hCG is a hormone produced by the placenta which shows up in the blood and urine as early as 10 days after conception. Its levels double every day for the first 10 weeks of pregnancy. Lower-than-expected hCG levels could indicate a tubal pregnancy.

You will be given a pelvic exam as well, to find the areas causing pain, check for an enlarged, pregnant uterus, or locate any masses in your abdomen. The doctors will probably also perform an ultrasound examination, which would show if the uterus contained a developing fetus or determine whether there are masses growing elsewhere in the abdomen. Unfortunately, the ultrasound may not be able to detect every tubal pregnancy.

There is also a more rarely used test for tubal pregnancy, called culdocentesis, which is used to check for internal bleeding. This test is performed by inserting a needle into the space at the very top of the vagina, behind the uterus and in front of the rectum. If there is blood or fluid found there, it most likely comes from a ruptured tubal pregnancy.

What can be done about my tubal pregnancy?
Treatment for a tubal pregnancy will depend on its size and location, and on whether or not you would like the ability to conceive again.

If caught early enough, a tubal pregnancy may be able to be treated with an injection of methotrexate, which would dissolve the fertilized egg and allow it to be reabsorbed into the body. This non-surgical approach results in minimal scarring of the pelvic organs.

A tubal pregnancy that is further along will likely require surgery to be removed. In the past, this operation would have required a very large incision across the lower abdomen, which may still be necessary in cases of emergency or severe internal injury.

However, modern technology has bestowed upon us an alternative method of removal. In many cases, the tubal pregnancy can be removed using laparoscopy, a much less invasive surgical procedure. The surgeon makes a small incision in the lower abdomen and inserts a laparoscope, a long, hollow tube with a lighted end. This allows the surgeon to see internal organs and insert other instruments as need. The tubal pregnancy is then removed, and the damaged organs are repaired or removed.

Regardless of which procedure is used, the doctor will want to continue seeing you regularly, to monitor your hCG levels, which should return to zero. This may take up to twelve weeks, but if the hCG levels do not decline, it could mean that some of the ectopic tissue was missed and may need to be removed using methotrexate or additional surgery.

How will this affect my future pregnancies?
About a third of women with a previous tubal pregnancy will have trouble conceiving again. This depends mainly on the total amount of damage and surgery that was done.

If the fallopian tubes remain intact, chances for a successful pregnancy in the future are about 60%. Even with only one fallopian tube, chances can be greater than 40%.

The risk of a repeat tubal pregnancy is increased with each subsequent tubal pregnancy. After your first one, you face about a 15% chance of having another.

Am I at risk of having a tubal pregnancy?
Those most at risk of having a tubal pregnancy are women between the ages of 35 and 45 who have had a PID, a previous tubal pregnancy, surgery on a fallopian tube, or infertility problems or medication to stimulate ovulation.

Some birth control methods may also increase your chances for a tubal pregnancy. If you become pregnant while using progesterone intrauterine devices (IUDs), progesterone-only oral contraceptives, or the morning after pill, you may be more likely to have a tubal pregnancy.

If you think that you may be at risk of tubal pregnancy, talk to your doctor about it before attempting to conceive. Although there is nothing that can be done to prevent tubal pregnancy, if monitored closely it can be detected early.

If you are pregnant and experience any of the symptoms of tubal pregnancy, contact your doctor immediately. Tubal pregnancy is just one of those things that you want to have checked out, even if you only have so much as a hunch. It can't hurt to be sure, and it may save your life.

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