The medicines have side effects, another group of drug problems. Some of May, the side effects of medication errors, while others are a danger to the inevitable use of drugs in an appropriate manner. An example of a drug, the adverse reaction to a mistake is the use of aminoglycosides or other nephrotoxic drugs concomitant medication in patients with moderate renal insufficiency, which leads to a deterioration of renal function. The "error" component on the situation between gentamicin, if the therapy is not justified. Another example concerns the administration of a derivative of penicillin to a patient with a history of immediate hypersensitivity reactions.

A medication error to use a drug without examining a contraindication or a particular threat to individual cases. If your doctor is aware of contraindicated or who have a particular risk and makes a decision for the drug from the benefits and risks, so there is an error of drugs. Instead, all matters relating to the use of drugs is a side effect, it can or can not be predicted and May or May not be avoided.

Unfavorable results or negative, did not respond to therapy or inadequate response to treatment. We need each case to determine:

(1) Is it appropriate antimicrobial drug (s) used?

(2) When the dose was chosen for the evaluation of PK / PD principles?

(3) If the duration of treatment is appropriate? and

(4) Patients who receive surgical treatment and support?

Choice and dose of the drug has already been discussed. The purpose of this article is not the administration of antibiotics and specific situations. One of the most common difference in the duration of treatment with S aureus bacteremia, evidence of metastatic lesions. In this case, at least 4 weeks of treatment is justified, but the management of patients with only 10-14 days of treatment continue to present the endocarditis and bacteremia repeatedly after initial treatment.