Drug abuse has a wide range of definitions related to taking a psychoactive drug or performance enhancing drug for a non-therapeutic or non-medical effect. Some of the most commonly abused drugs include alcohol, amphetamines, barbiturates, benzodiazepines, cocaine, methaqualone, and opium alkaloids.

Drugs like cocaine, methamphetamine, marijuana, heroin, alter gene expression and brain circuitry. Once drug abuse crosses into addiction, the compulsive drug craving, seeking and use occurs. Our featured publications offer a variety of cultural, social, and scientific views on drug abuse.

The use of chemicals to alter the way we feel and see things is one of the oldest activities of the human race. But a person's use of a drug such as tobacco, alcohol, cannabis or heroin can become uncontrolled, or start to control them. Even when the use of drugs leads to serious physical and mental problems, the person using may still not want to stop. If they do decide to give up, they may then find it's much harder.

A drug is any chemical that produces a therapeutic or non-therapeutic effect in the body. Chemicals, on the other hand, are a broad class of substances -- including drugs -- that may or may not produce noticeable effects in the body. Many chemicals (such as tin, lead, gold) have harmful effects on the body, especially in high doses. Most foods are not drugs. Alcohol is a drug -- not a food, in spite of the calories it provides. Nicotine is a chemical that is also a drug.

Alcohol, amphetamines, barbiturates, cocaine, methaqualone, opium alkaloids and mild tranquilizers are some of the substances that are most widely misused. The use of these substances brings on criminal prosecutions against the user, apart from the obvious physical and psychological damages. And add to it the social discrimination that will follow.

Many people see drug abuse and addiction as strictly a social problem. They tend to characterize people who take drugs as morally weak or as having criminal tendencies. They believe that drug abusers and addicts should be able to stop taking drugs if only they were willing to change their behavior.

Continuing to use drugs even though you have health problems that are affected or caused by your drug use. Associating with questionable acquaintances or frequenting out of the ordinary locations to purchase or use drugs

Focusing recreational activities around obtaining drugs, using drugs, or recovering from drug use.

Believing that you no longer have to worry (complacent). That is, that you are no longer stimulated to crave drugs/alcohol by any of the above situations, or by anything else - and therefore maybe it's safe for you to use occasionally.

Reinforce the message that alcohol, tobacco and other drug use is a serious matter - and is not tolerated.

Being in the presence of drugs or alcohol, drug or alcohol users, or places where you used or bought chemicals.

Using prescription drugs that can get you high even if you use them properly.

The line between substance abuse and drug dependence is defined by the role drugs play in your life. Addiction and drug dependence occurs when drugs become so important that you are willing to sacrifice your work, home and even family. Once your brain and body get used to the substances you are taking, you begin to require increasingly larger and more frequent doses, in order to achieve the same effect.